If you like C# then use C#.

I think there are some people who see C# as a "Microsoft Thing" and won't have anything to do with it.

As for Python, I don't particularly care for it, but many people find it to be a satisfactory language in the sense that you find C# satisfactory. That is, there are lots of good libraries that you can do to get many tasks done quickly. Performance doesn't matter much in applications that are limited by network latency, disk I/O or waiting for database calls to come back.