To answer a few questions posed here: 1) It worked great for me, but we were doing a very simple presentation type app
2) grunt-node-webkit-builder is pretty great, saves ~15 minutes for each build, grunt takes a little bit to get going, but is easier than most php / ruby tools I've used
3) You don't have to use Angular, Jade, or Coffescript
4) While I did not take advantage of using a database, I suspect someone else has and it's not a big deal.
Also for anyone interested the same code we ran through node-webkit, worked well with build.phonegap.com, which means it would also work with Cordova (http://cordova.apache.org/) adding mobile device support into the build process would be very impressive, as would a node-webkit GUI build tool.
If I had all the time & attention span in the world, combining a node desktop+mobile build tool with an IDE like light table into a complete package that had a simple installer & GIT integration would be pretty great, and mostly assembling parts instead of re inventing the wheel.
However, I have bills to pay so I need to get back to figuring out how a big corporations's imaginary friends will make purchasing decisions ;)