It depends on each manufacturer's implementation. The ever-growing complexity needs to be managed, both in learning curve as well as overall placement and design of features.
For one, BMW does this right. The large screen is controlled by the iDrive knob in the middle, which rotates with haptic detents, is pushable, and has 4-directions on it. All of the major controls are still present with physical controls: radio volume, presets, dual temp control, fan speed, vents, cruise control, phone, etc. The only time you would regularly use the iDrive is for navigation, which is always going to be kludgy because of the complexity of putting in addresses. I welcome voice and touch here.
http://www.moibibiki.com/images/bmw-4-series-interior-12.jpg