What do rate limit by? There's billions of IP addresses a spammer could use, captchas can be solved by offshore farms, there's almost nothing to go by.
But "for these businesses every connection from certain continents is an attack" is absolutely true.
I've worked with these businesses, worked with their CEO on their business needs, and seen their internet traffic. They, really, have absolutely no need to interact with Asia. They aren't hotshot SV companies trying to become the global leader of VR selfies, they are just boring[1] businesses sending plain old physical goods to customers within a thousand miles of them.
[1] Boring isn't a pejorative in my mind, but I know it is for some other people.