This is the argument I see everyone using, but I don't understand it. Why does it matter if a spammer knows your address is valid, if they've already decided it's valid enough to spam it? Do you think spammers really bother to validate their address-lists before reselling them to other spammers? (Even if they do, though, I think it'd be irrelevant. If your spam filter is effective, it doesn't matter how much "true spam"--things you have absolutely no chance of finding interesting--you get. It all gets filtered away before you see it.)
Think about it this way: if there was an auto-unsubscribe mechanism, which ethical bulk email senders honored and spammers didn't, then it would become much easier to filter spam: any message that clusters into a message-cluster that the system has sent out an unsubscribe-request for already, is junk.