Hate to see what happens when a bug causes the wrong motors to fire and the thing breaks all of your bones. Be awesome to use one though all the same.
The thing that I find more worrisome is the fact that little squishy people will be handling things that are so heavy that, if fumbled, would carry enough momentum to rip right through them. Imagine letting a 250 kg piece of metal slip -- if it hit your flesh, that's a problem. Once the strength of these suits gets high enough to handle loads like that I think we'll have to see more actual exoskeleton armor to protect the pilots.
I sure wouldn't want to drop 100kg of weight on my foot from 1 meter :)