really any "outdoorsy" city -- Denver, Salt Lake, Seattle, Juneau, Flagstaff, Jackson Hole, Bend, Asheville -- is going to be hard to replace. Even with another city from the list. Seattle's mountains aren't really the same as Salt Lake City's mountains, which aren't really the same as Denver's mountains (I have lived in or near all 3 cities.)

And of course if you're working remotely, you can live in a much smaller town that can't be replicated in any way. There's no way to replace "I live in my grandpa's hometown" (Milo, MO -- not a place I want to live, but if I did, there would be no replacing it.)