I heard a while back that to be the biggest winner, you need to be in the nano-second range for your latency (for example, you would need to rent server space at the stock exchange and not be running any firewall/etc to have minimum latency) ... I don't think that he is talking about the large players in his articles because he is still in the millisecond range which is very slow for this purpose. In 2011, microseconds were apparently for big players (http://www.youtube.com/watch?v=kjIdzBtTBnI)