Yes, I could see many organization adopting only the Mongo and Angular portions of this stack and leaving their API to leverage the .NET Web API; it too is RESTful.
Again in a lot of ways though those are a response to Node.js and socket.io
All of your points stand: how expensive it is, the fact that it is a bit heavy, and not homogeneous.
I still think it will evolve and will not fall behind like Java etc. but it does not hurt to hedge a bit and start learning the "MEAN" stack :-)