However, the irregular tiles actually bother more than if it was a standard geodesic sphere which only had 12 pentagons. For one, the fact that tiles are different sizes looks kind of weird. More importantly, this tile layout could actually make an important strategic difference (much more than if there were only 12 pentagonal tiles). Assuming movement costs between adjacent cells are constant, a straight line may not be the fastest way between points anymore! Looking at the heavily distorted mesh example, I can see several places where a path through a few large cells has the same movement cost as the straightest path.
Also, a realistic simulation of global wind patterns isn't actually that hard. Since it's only long-term trends that matter (at least when it comes to shaping overall climate), it's not like you'd have to calculate detailed fluid mechanics models. A simple model of Hadley & Ferrel cells (which is key to having realistic deserts) would get you most of the way there. [1]