All your affiliates care about is that your conversion and commission rates are higher than the competition. All you need to care about is that your lifetime customer value exceeds your costs including commissions.

A great example was a dating site that offered a 200% commission on each sale, because they knew that once people were in their sales funnel, enough would buy buy bigger ticket items to make it profitable. They crushed the competition who was offering 50% commissions on similar products because affiliates chose to get the 200% commissions.