I expect in the next decade or so, sensors and microrobotics will become good and cheap enough that mechanical pest control will outcompete chemical: finding and squashing the bugs with inhuman reach, patience and thoroughness. Of course the tiny exterma-drones may be pretty creepy-looking, themselves.
I could picture one implementation being a skirt/kill-zone around a bed, such that any bug that feeds is definitively killed before it can return to nesting/breeding spots. So the customer is still the bait... but they quickly win a war of attrition against any local bug population, unless it's being replenished from elsewhere.