At that point you're better off just writing the functionality you need from scratch - which was basically the coding standard when I joined Google Search in 2009. They've since moved to allow Closure, which was a big win for developer productivity, but OTOH the latency of the SRP has roughly quadrupled since I joined Google.
Anyway, I'm firmly in the "you don't need JQuery" camp now, since most of its functionality is trivially implementable in one-liners since IE9+. I'm unlikely to go back; I've been using vanilla JS for prototypes for the last 2 years and am using it for my startup now, and have yet to encounter a case where I really miss JQuery. It was a very different world in 2006 when I learned it, or even in 2009 when I joined Google.
Also, I suspect that the overlap of people that use Closure and those that use JQuery is near zero, hence why nobody in the JQuery community cared about CCAO. Both of them are highly non-typical Javascript, as is Angular. JS shows its Scheme heritage in that somehow every major framework results in completely different, mutually-incomprehensible code.