Lots of opportunities throughout the rest of the stack too - from novel architectures to on-chip programmable logic, the end of Moore's law puts more pressure on some really interesting innovation.

eg Rainbow[0], BORPH[1], Mill architecture[2]

[0] http://www.hindawi.com/journals/ijrc/2013/789134/

[1] http://borph.org/

[2] http://millcomputing.com/docs/