Everything that matters about vdev size and configuration is explained here, complete with charts that indicate the actual overhead of different arrangements: http://blog.delphix.com/matt/2014/06/06/zfs-stripe-width/
"TL;DR: Choose a RAID-Z stripe width based on your IOPS needs and the amount of space you are willing to devote to parity information. Trying to optimize your RAID-Z stripe width based on exact numbers is irrelevant in nearly all cases."