Besides having to transfer data to run the application in the browser, what limitations are inherit in a web-based application? (I acknowledged the data transfer limitation in my previous comment).

Browsers (especially mobile browsers) are unnecessarily limiting what can be done on the web. Adding additional permissions could enable browsers access to more system resources and components, especially on mobile.

Could you provide some examples of applications that don't require a lot of data that couldn't be run in a web-based environment, because of physical (and not current browser or software) limitations?