I tried this. The problem is the HUGE amount of cash you have to put up up-front to just get devboards and datasheets. Also, while BT/WiFi licensing is pretty straight-forward, GSM licensing is not - and don't forget the licensing costs for the chips...
Furthermore, the more functionality you want to embed on your board (I intended on a ethernet+poe and a powerline/power supply board, linked via MII to the CPU), the more layers you will need on the board.
And RF engineering competence is a must both for functionality and for EM radiation compliance, and this is not cheap too.
Altogether a too small market.