I've heard several male scientists in cosmology suggest that Rubin either discovered or was instrumental in the discovery of dark matter.
This was a profound and fascinating experimental result: galaxies contain much more mass than can be accounted for by observable matter. The implication is that the observable (baryonic) matter in the universe is only a small fraction of the actual mass content. This is remains an unsolved problem in cosmology.
I know that even today the LHC is running at higher energies in part due to an is interested in explaining dark matter through the generation of WIMPs and other massive particles. So this remains a very interesting question in physics.
Despite her thought providing result, she is not a well known scientist.