A long time ago, Dave Taylor left id to create Crack dot Com. They then wrote the game "Abuse" using C++ and a lisp variant:

https://en.wikipedia.org/wiki/Abuse_(video_game)

http://lispgames.org/index.php/Abuse

Although, from the FAQ:

http://abuse.zoy.org/wiki/doc/faq

"Approximately seven percent of the game engine and Abuse combined is Lisp code. The rest is C++."