Urbanite here (Manhattan),
Have turned down offers/interviews at many companies because of non-urban location. FB/GOOG at least have urban offices, Apple does not, as much as I admire their products and would like to work on them.
Even when I lived in SF I'd routinely turn down interviews for peninsula/south bay companies because of the location. Fortunately there is no shortage of good quality jobs in my specialty in both SF proper and NYC, so I don't think I've ever been in the position of choosing a poor job in an urban area vs. a great job in a suburb.
The fact that it's in a suburb is less of a factor than the commute. Even with fancy-schmancy shuttle buses delivering you from the city it's still a giant pain in the ass. Right now my commute is a 15-minute walk where I can pick up coffee along the way, or drop into the gym which is midway between work and home. Spending 1+ hrs cooped up on a bus, even a nice bus, sounds downright nightmarish.
I already work full-time, I want the remainder of my time to be my own to do with as my please, as much as humanly possible, and long commutes are the antithesis of this (and yes, save the "but I'm productive on my laptop on the bus!" or "podcasts! audio books!" arguments, I've heard them all).