I've been really unsuccessful at getting a Pi to not destroy SD cards. Good quality cards, good quality power supplies, no swapping - it still eats them up.

The best way to fix this is to put the actual OS on an external disk. You absolutely must bootstrap from an SD card, there's no way around that. But that can be entirely read-only and then you bounce to the external drive. Or maybe you could do something like a PXE boot instead - copy a system image down from a server and boot that. Personal opinion, this is the only way I would try using Pis on a long-term basis.

The Jetson TK-1 board from NVIDIA includes a real SATA connector. Because it's GPGPU-capable it's also vastly more powerful than even a Pi2. It also has USB 3.0 so running swap on a memory stick would be much more performant.