1996

> Don't think that the guilt you feel is something other people feel. I can assure you I feel nothing.

> It's unfortunate, I recognize it's wrong, but at the same time... I don't actually care.

Same for me!

Competing theories for where engrams (physical memories) are stored:

- neuronal network / synapses

- microtubule network in inside the neurons

- now RNA recently joined the competition

As microtubules are protein, so made from RNA, this experiment can not exclude microtubules

My guess: everything plays a role: individual neurons encode internally bits of information (like an inode), while the multidimensional network of neurons creates the structure (like the filesystem), while electrical impulses on the network are commands (like software) both made from files, and accessing some other files.

The more advanced animals have more advanced filesystems with partial RAID1 mirroring (experiences removing fully one hemisphere) and caching (we know that's mostly the cerebellum job for movements).

Sleep is both a log replay/filesystem scrub and defrag (committing memories to long term storage if they are frequently accessed)

Should Iran also investigate if Iranian residents trade on Binance? And if they do, why is it Binance responsability to bow to the Iranian government? And if they don't bow, why should Binance bow to the US?

Conclusion: Team USA: world police.

> > In case you find it useful, I'll mention that I use Bitcoin as a store of value: it lets me store a portion of the output of my production (i.e., my salary) that I don't need to consume right away. Occasionally, I convert a portion back to other currencies and consume it

> But why use Bitcoin for that? You could use GME shares and get the volatility without the crazy power usage, or use a stable ETF.

Because if you plot the BTCEUR, the EUR ETF of your choice, and GME *USDEUR over the last 10 years, and apply a moving average equal to your financial buffer (say 6 month), you will see one is clearly trending up: BTC

Someone who put 1% of their income or use DCA to regurlarly buy an equivalent amount of BTC, GME, any ETF will quickly find than the BTC represent 90% of their saving, meaning it grew much faster than anything else.

It's not the volatility or the greeks, but the time trend if you can afford to delay your spending!

If you spend 2/3 of your saving to acquire something that you realize is worth 9 times less than what the other 1/3 of your savings purchased, you quickly stop and reevaluate your automated purchase decisions!

Do not worry too much, China is getting stronger every year.

As for the US dollar, we have a potential replacement that is enjoying global acceptation, while most of the mining is in China.

I am Chinese too and like you, I usually don't bother with pirating since it's a lost of time.

> I hope they are not proud about it.

But like the parent post I have no shame or guilt in not paying for content. And I'm proud about being clever!

It may be a mentality, as I do think people are stupid to pay for a DRM ebook while libgen has it without DRM. But if it takes more than 2 minutes to find it, I buy it.

Google is the new Yahoo: where acquired startups go to die.

> Either way, you want to generally avoid C-c for copy in terminals because it's already bound to the all important "send sigterm signal to foreground process". This is on a long list of ancient cruft that exists in terminal emulators and shells.

stty intr ^X

Then ctrl-c will no longer bother you, and your muscle memory will quickly adapt as X is very close to C

> Reading your comment history, you seem to wear your selfishness and contempt for the poor as a badge of honor

Indeed. If there is something wealth didn't change, it's my selfishness - just as much before as after!

Unfortunately, it is like in Harry Potter: you can only get some if you don't want some :) And yes, I have thought about giving it all. I would change nothing: I would make money again and find myself just as empty, with the same problem, except with less of my prime years to live and find a solution.

BTW, you made your account in 2012. You have know about crypto for 9 years. If you had invested even a hundred dollars in 2012, or the next year you would not need to ask. HN has a lot of blame for the number of bright young hackers that were discouraged to invest in crypto.

> it assumes that you, the current holder of the money, are more responsible than those other folks.

I don't know, but I have a track record of success, while they have a track record of failure, so I am a bit doubtful it will change.

For example, I have a very deserving friend. I want to make sure he succeed. But I will never give in any crypto, as it would sell it the next day because he is afraid of variations. Likewise with money.

Instead, when I hear he is struggling, I hire him to perform some work that will benefit him in his carrier, to gently nudge him while providing money but not as a gift since in my experience it breaks people spirit.

> I also think you're getting a lot of downvotes because you are speaking from a very unsympathetic position, but it is an interesting discussion so I'd urge you not to get discouraged.

I am a bit- I have tried keeping a simple message for years to people who want to make money - before the last bull market, it was something like invest 1 or 2 grands in crypto, just money you can afford to lose, it will get you a brand new car (feel free to check my posting history, I don't remember the specific wording)

I even said that to arcticbull, who frequently diss crypto here.

And a few month later, those who listened got their car. Most people thought I was talking funny. It was lost on them. I find that very sad.

> If that's not an option then there are a number of good and responsible charities

I am now convinced money will do nothing, whether you have it or not, or at best very little. What matters is foresight and leverage, to convert your ideas into implementations. Leverage can be obtained - VC do that if you have charisma.

Fortunately for me I will not need them, as I am low on charisma! Still, biotech will be the next boom - whether it is augmenting humans, curing cancer, achieving immortality, it will bring lot of happiness.

This is interesting and I can help make it happen. It will help many orders of magnitude more people than my money could. So I am learning biology. Hopefully it I will help me infuse money at some very precise chokepoints where it will be able to act as a positive enabler. In crypto, I saw that happen by people who have built the likes of coinbase.

You can peddle your communist propaganda somewhere else comrade

> I would love to hear stories to the contrary before I make the commitment.

And this is exactly why I wrote this comment. People here are looking to get rich without asking enough questions like "why" or "what then?"

Make a few millions if that's what you want- why not? But it won't make you happy.

Stay away from drugs. Keep doing things that you find interesting and bring you joy. Associate with cool people. And don't say "f you" too much because social connections and a few obligations here and there are what make life fun.

Islands is a common trope. Have you tried living on a tropical island? The weather is pleasant, the food is nice, but it gets boring after a while. There is little to do, and it's really hard to relate with the people who live there: none of them are into hacking or computers.

As for gambling, I've never enjoyed that.

> Why not throw $100 billion into nuclear fusion research?

Because I don't care?

See, you have things you want, things you care about. Then you get them. And eventually there is nothing you desire anymore. Feel free to not believe me if you prefer but that's the cold hard truth.

Biology is the only thing a bit interesting to me. If I didn't have that, I think I would just slide into drugs and eventually OD. The sad story of Tony Hsieh acted as a stern reminder I had to keep my new path.

> I'm confident I could spend the entire world GDP if I had it. I'm not saying I could do it well, but I sure as shit would have fun doing it.

I don't know your goals, and I don't judge them, but if you are trying to get rich (as a lot of people on HN seem to desire) this mindset may be counter productive.

I didn't have the mindset that spending was fun when growing up (asian parenting...) This may be why I didn't spend anything when bitcoin crossed the any of the various price points.

There may be a selection effect: those who end up making over 6 digits of net worth are less likely to enjoy spending - and the more extra digits, the less likely.

Someone on this thread was saying they enjoyed seeing 7 digits in their account this year - I guess they sold at minimum 200 coins. Given the current price path, it's likely to break 150kUSD this summer. So if they had waited a bit, they would have been in the low 8 digits.

Those who sold when the $1 psychological price was passed got themselves a few meals, considering the same amount.

Do you see where it goes? I'm not advocating hodling, because there is a point where you have enough money for anything you want - but I think it's not true for the kind of people who find spending fun, and by consequence were driven to sell early.

This is so wrong - like the suggestion of giving it all away (even if I quickly considered that).

Money is not the problem, even if it contributes to it. Money is just an enabler. Money reveal your deepest tendancies. Remove it and you are back to square one.

In the past, when I was as naive, I gave some money to people: most people focus about tiny problems (the dishwasher broke!) that are easily solved with a few hundred or thousands.

Then I saw first hand how money is just an amplifier of human beings, and how it can help some people with bad tendencies destroy themselves - starting by teaching them effort is not necessary.

I don't give anything to anyone anymore. I learned before I did too much damage. I moved and broke contact.

> And there's no limit to what can be done with enough money.

Actually, there are: coming from your imagination.

So I'm learning biology. When I'm done I won't bother with a postdoc but just start a research lab (or buy one).

It has helped me feel less empty, but the pandemic did hit me badly.

> I’d rather be doing if I didn’t have to work everyday.

For a while, then it would lose meaning.

I tried not working, it made me feel very empty inside. Human need goals. We aren't made to be idle for a long time.

I'll try to explain that better: "Fuck you" is when you refuse or sever a social connection. Don't do it too often. Because when you don't need any social connection, you have successfully create your gilded cage.

I've learned from my mistakes: Now I'm still retired but I work here and there, doing consulting or helping people, and learning biology.

It feels much better.

Missing part: the sadness of having too much fuck you money - like if you don't have to work ever again.

When you have more than you can spend, many things lose meaning.

> In europe cinammon is mostly used in desserts so some dishes that use it in India can seem a bit off putting at first, but the truth is, that it has a great pairing with many dishes. Being unused to something and calling it bad are two very different things.

Can you suggest something that goes well with Cinnamon?

It's one of the spices I find the most intriguing! So common for desserts, even in the US, but not for savory food!

So true. HN often admires complexity for complexity sake.

Even without cloudflare, a static website on 5 VPS from 5 different provider on 5 different continents with a Round Robin DNS and a low TTL will get you most of the bangs for bucks

Add geoIP to the mix (like from Azure) and you're golden, even if you are just scp'ing files to 5 VPS.

If a DC burns down, remove the A record (or even better: have a script do it for you) and reroute to the remaining 4.

Extra bonus: you can fire the DevOps team :)

There is going to be complex behavior (adapting to traffic by routing around it) that a simulation will poorly predict

Also, you will have correlation between adjacent segments of the network- and the idea of extracting "rush hours" brings its own set of problems.

Consult with a statistician familiar with geographical models. I'm sorry I can't help much more than that. It's very different from finance.

Do you have as many events in both samples?

If not, even if you measure the same thing, the variance may differ - you can start applying the law of large numbers since you mentionned "millions" and just consider a normal distribution, but for rare events you need something different (Poisson)

Are the series static? If not (ex: temperature) you will have to model on time. As the link mentions people crossing intersection, I assume more people will at 9am than at 2am (7 hours ago). Likewise if one series is a weekday and the other a weekend, you may have surprises!

You have to consider other things (ex: day of the week).

I would recommend avoiding the problem altogether: fit something (KDE, ARIMA...) on your timeseries, and plot the fit with the 95% CI from X=0 to X=24

Do the same for the other series, from X=0 to X=7 and see if they are at least in the same CI

Then compute the correlation of the 2 fits (just to have a reference number) and use that as a metric.

So true. This is why the US is so much better than Asia.

What worries me however is how there are more and more laws and regulation to not let people crash and burn - like forcing people to have health insurance. Stupid code for building houses - etc

EDIT: and I'm not being sarcastic. I admire how by taking the correct decision to apparently sacrifice the poor, we have made the pie bigger for everyone including the poor (unfortunately, as noted by a comment below about Des Moines, building code is quickly changing that)

Your best interest may differ from doctors best interest when treating you (not getting sued, following guidelines, getting paid for not rocking the boat)

So document yourself: medline is free, and with sci-hub, you can get the full versions of anything

EDIT: actually, no, don't document yourself. Ignorance is bliss. Why would I even care? After all, it's your life! And I care even less than your doctor, since we don't even have a contractual relationship (which you have with your doctor by virtue of paying him).

I notice the downvotes to my post, but what you was told is demonstrably wrong.

As for how/why it works:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069085/

"Fasting before or after wound injury accelerates wound healing through the activation of pro-angiogenic SMOC1 and SCG2"

There are various other publications on autophagy (removing old stem cells and making new ones)

For those who are going to say "in mice", the effects of true (water only) fasting has been replicated in humans, in well done trials, in even harsher conditions than surgery: chemotherapy.

Fasting improves various things such as the severity of symptoms during chemo and the efficiency of the treatment:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921787/

"Short term fasting during chemotherapy is well tolerated and appears to improve quality of life and fatigue during chemotherapy"

It may be counter intuitive, but there's a large body of evidence that fasting promotes healing (check the various reference of this 2018 trial: "Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy" https://pubmed.ncbi.nlm.nih.gov/22323820/ etc

Related: the surgical scars of fasting mouse heal better (various publications report the same results)

The same seems to apply in human, with various individual anecdotal report: https://www.quora.com/Did-long-term-water-fasting-improve-an...

> the reality is that as a poor white person it is much easier to find your way out of poverty.

You misunderstand. The comments are not about race, but the individual decision that's always available to you, to break away from a losing game.

Likewise, I was dragged down by my family who defined what I should aspire to (ex: being a doctor or a professor or a lawyer while I liked computers) and what I should do (ex: give them money to help them). I tried to do what I was told and realized it caused failure.

> which allows other members of your family to likely not be poor — thus able to support you.

After noticing and analyzing the pattern of failure in my family, I decided it would stop with me - by disassociating from them.

From your post:

> That is why it should come as no surprise that so few Black people have successfully built generational wealth: we’re always actively trying to keep the current generation alive

That's your mistake.

Eventually, I decided "screw them, I don't give a flying fuck even if they starve to death" -best decision of my life!

Yes, it involved a lot of risk, as I knew they would never help me again in return, but being in the US it was almost a given I would never return.

Now I'm a young retiree.

I was asked money- more than once, especially after they knew I had made it. I told them in very clear term I'd rather burn my money and become a bum than give them a single dollar. That stopped the claims :)

> That’s why the American Dream is so far out of reach to many: https://andrew.im/essays/a-journey-to-the-american-dream

You're so wrong. The American Dream is out of reach because selfishness is unfortunately not taught. We give people wrong values (help your friends, support your family etc) and act all surprised they fail in life.

It's a honest mistake to make- the same as having kids in the hope they will help you in the future (they might) while they will certainly cost you in the present and the future (they sure will)

> The Qubes people don't recommend doing GPU passthrough because of the security implications.

Why? DMA?

And to do that, a TPM is needed to keep the keys/signatures

Where do you live? How is that possible?