HNHacker News
TopNewBestAskShowJobs

8iterations

56 karma · joined March 27, 2011

I'm a biochemist by training, and bioinformatician by trade.
submissionscomments
8iterations··on Ask HN: Who is hiring? (October 2025)
Jäntra Biosystems | Multiple Roles | San Francisco or Remote | Full-time | Salary + Equity

Jäntra Biosystems is revolutionizing protein structure prediction. We’re building AI models at the intersection of biology and computation. Join us as we unlock life’s molecular machinery.

Open Roles:

- AI Systems Engineer (C++ / CUDA / HPC)

- Structural Biologist / Bioinformatics Scientist (Cryo-EM / AlphaFold / Data Analysis)

What we’re looking for:

Engineers & scientists passionate about AI and biology. C++/CUDA expertise (AI Systems Engineer) or structural biology experience (Bioinformatics Scientist). Familiarity with HPC, GPU clusters, or structural prediction tools (AlphaFold, cryo-EM, etc.).

Why Jäntra: Competitive salary + equity San Francisco or remote Small, fast-moving team Work that matters: advance our understanding of life’s building blocks

Apply: https://jantra.ai/jobs.html email: hello@jantra.ai

8iterations··on Dead Startup Toys
atrium was really bad my dude.
8iterations··on MTV VHS Recordings 1981 to 1989 [video]
Totally Rad!
8iterations··on It’s Time to Build
Exactly, him & his firm have been leading the bandwagon on crypto investments, social/mobile, ads, "scooters", and all the other sectors which are all hype & no build.
8iterations··on Ask HN: How are you preparing for COVID-19 disruptions?
Yes I agree with you, I am concerned with the elderly & infants. As these are the demographics which usually have higher fatal outcome both in diseases, and even adverse effects from drugs/surgery.
8iterations··on Ask HN: How are you preparing for COVID-19 disruptions?
I was wrong about the season flu being less deadly. However if we look past lay press like CNBC or The Atlantic because this is cutting edge/developing research, and into the academic press, we see that the mortality rate is significantly lower than other outbreaks like SARS & MERS (9%,35%) https://academic.oup.com/view-large/figure/199362642/dyaa033... https://doi.org/10.1093/ije/dyaa033

So it seems prudent to reiterate that the only causes for social disruption & need to prep would be to have unjustified panic and run at stores like the behavior seen in Italy.

8iterations··on In a First, US Doctors Use Crispr Tool to Treat Patient with Genetic Disorder
We make a variant caller, which is used in the pipeline for this kind of work, you might find it an interesting rabbit hole. https://magnolia.sh
8iterations··on Ask HN: Who is hiring? (October 2018)
Lucid Align | SF or Remote | C# Xamarin | Full-Time or Part-Time | https://lucidalign.com

Lucid is a scientific desktop tool for genomic sequencing data. It's part of a larger toolset used for sequence alignment, variant calling, and annotation. Pretty much inspired by Sublime Text, for sequence alignment maps (sam files).

Looking for someone to fix some bugs and refactor where necessary. If you have fun working on this, the larger toolset is in C++ and uses Caffe2, so you can try your hand at that once this work is completed.

If you are nearby and want to meet up, or faraway and want to chat just hop into the discord channel.

https://discord.gg/KcggEhk

Make Scientific Software Great Again!

8iterations··on Twitter did not suspend Alex Jones or Infowars
"Conjectures and Refutations: The Growth of Scientific Knowledge" is my favorite work by Karl Popper. His 1945 work on the Paradox of Tolerance seems more appropriate here.
8iterations··on The life cycle of HIV in 3D [video]
A better animation is the winner of the AutoPACK challenge few years back: https://vimeo.com/62635232

Those guys did an awesome job because: a) use of brownian motion b) sick af music.

8iterations··on To detect cancer we turned genomes into images and put them through DCNNs
Traditional variant calling, that is bayesian methods, have gotten very good at detecting point mutations, that is single letters. But have hit a wall when it comes to more complex structural mutations, we wanted to build this for example to focus on driver/passenger mutations in tumor/normal samples. (check out the "Preface" post for our LSTM version, and the logic behind this)
8iterations··on To detect cancer we turned genomes into images and put them through DCNNs
Hey, I'm one of the guys working on this. These are just our notes and drafts, and even though we are at ~97%-99.3% the goal is to get to 99.9587% or higher because out of 3-4 billion letters that is still significant. Here's a cool non-technical magazine article about it https://twitter.com/EricTopol/status/922315550054793216
8iterations··on E.P.A. Dismisses Academic Scientists from Major Scientific Review Board
I see you are just a random developer guy, so I would recommend you talk to your friend more. Then, improve your skillset in the sciences, so that you may outsmart him/her and put whatever resources they possess to better use.
8iterations··on Ask HN: Who is hiring? (February 2017)
San Francisco | Full-time | C++/C#/Xamarin

Genomics it's good stuff. We made some tools that are better than what academics/gov/big companies make.

Desktop applications, not web or "cloud"-- b/c you make video games and movies with desktop applications, so maybe when lives depend on it skip the web browser.

Anyways you'll get paid market-rate and get to work with fun technologies.

You can email me: mo_r [at] me.com

8iterations··on How to Fold a Julia Fractal
Can you place links at each of your figures so that we can directly link to those of interest? This is great stuff!
8iterations··on The Sierpinski triangle page to end most Sierpinski triangle pages
I was going to say not all Sierpinski pages, because I didn't expect to cover CGR with genomes. But it covers it! My version: http://8iterations.in/cgr_hanako
8iterations··on Ask HN: Who is hiring? (August 2013)
Is it possible for me to stay in SF? Can travel a bit.
8iterations··on Biohacking at SHDH45-Google
Any specific advantages? I'll try to check it out.
8iterations··on Biohacking at SHDH45-Google
Yes exactly, they held my hand through the whole copy/paste process.