75 karma · joined September 18, 2013
As others have pointed out, the risk/benefit calculation here is extreme: a few bad reactions per million vs. a disease that has already killed more than 1000 people per million population in the US.
Interesting point about Bayesian methods, whenever there are potential flaws or additional uncertainty, it's better if they are more explicit to prompt thoughtful interpretation.
I have seen outrageous examples of "accepting the null hypothesis" many times, but many negative result studies have great value and even a single negative study can provide evidence against a very large effect.
Volume 2 is more difficult but also very good.
Don't forget that you always read mathematics ( or probability theory ) with a pencil in hand. It's a participatory activity.
https://archive.org/stream/SolvedAndUnsolvedProblemsInNumber...