JimtheCoder

If we could diagnose before actual Parkinsonian symptoms emerge, studying and developing preventative strategies and pharma will be a lot easier.

Parkinson's is funny in that sometimes what initially presents as Parkinsonian symptoms could develop into something like MSA over a span of 5 or more years. If this person were in a clinical trial for pure Parkinson's, it would sort of mess things up...

"They do zero efforts to help the public understand anything."

To be fair, with complex diseases, the experts don't even understand them fully...

Trying to explain something super complex with incomplete knowledge to most humans, who often don't have even a basic understanding of how biological systems work, seems like a bad idea...

"Would public venues allow soon-to-be dementia patients line cutting priority etc? Think amusement parks, transit reservations, hotel booking, bars, movie theaters -- all of it. There could be a whole industry built overnight of catering to this specific demographic."

Do we do this for people with cancer?

"I've read that because Parkinson's is caused by the death of dopaminergic neurons in the brain"

Not to nitpick, but it's my understanding that we all lose dopaminergic neurons in the Substantia Nigra as we get older. Some people lose them a a lot faster, and they develop what we call "Parkinsons". There is also presence of Alpha Synuclein in the dysfunctional dopaminergic neurons, which are not generally present in the "non-parkinsons" population...

"but a sport where things like the exact composition of dirt is critically important."

Let's not swing the pendulum too far in the opposite direction either...

Yes, I did read the article.

Devon, in his 20's, makes $150k per year, was an intern at Google.

You don't think the people at Google could narrow it down a bit and figure out who it is?

I know if I was making $150K working one hour per day and spent the rest of my time working on a startup, I would not want an article written about me and published on the internet...

This does make for good media, but does anyone believe that adding one more cook to the kitchen at Google is going to measurably change their trajectory in this area?

"It would be hugely embarrassing to go back to working for any other company. I would have been much better off financially if I had stayed at my high paying dev job."

Well, you can be broke and keep on doing something that clearly isn't working for you...but maintain your pride in doing...something that isn't working and being unsuccessful.

Or you could be "embarrassed" with a high paying dev job. But honestly, that is all in your head. No one really cares that you failed and came back to a high paying job. Nobody is thinking about you that much.

IMO, stop doing things that aren't working, work for someone else for a while, get some money, recover, learn why you are not being successful building your businesses, and maybe try again...?

You mentioned in your other post about we need to stop immigration and send the temporary visa holders home.

Isn't doing this introducing more economic distortions?

This sounds like a horrible idea...

Kick out the foreigners is not something I would expect to hear on HN.

"Obviously, Canada needs better housing and immigration policy, but I’d call those pretty minor and resolvable problems for a country that is doing so well."

And your solutions are...?

I wish we still had headphone jacks so I could use $10 disposable headphones from Best Buy...

And the rule that Tik Tok is clearly breaking is what? Being Chinese?

"Can only think the feds regret not banning it long before anyone had heard of it"

But if no one has heard of it, then no one would be using it. Why would you ban something that no one is using...

I still don't understand why people are so in love with this song.

It seems a little astroturfy to me...

"A model has no objective. It has only output."

Is creating output not an objective?

Surprisingly, they didn't add the "You get to pay overly inflated housing prices, just like SV...but with drastically lower salaries" selling point either...

If you have never seen anyone in your gym bench 2 plates...well...I am not sure what to say to you. Maybe find a different gym?

The person I was responding to is talking about SS, why 5/3/1 is more appropriate, and things of that nature.

If he MAXED out at a 225 bench, a 325 deadlift and a 275 squat, he has no business really talking about this sort of stuff. You don't even need a structured program to hit those numbers...you just need to do it.

"At my peak before a recent injury I was at 225 bench, 325 deadlifting and 275 squat."

So you barely lift...?

"If accurate, that means more than 25 percent of accounts on the platform follow Musk."

Remember Tom from MySpace? I wonder what percentage of accounts followed him...

Maybe Musk is using the same strat for success...

I watched this a while back. Or at least, I tried to watch it.

In my opinion, it was incredibly pretentious - so much so that it made it hard to listen to.

Just read the book instead...

"Do you have data indicating that the politicians who don’t focus on the subject are more modest with their travel?"

Why would they be if they don't care as much...?

No. Why would it?

To be fair, blaming these wildfires on global warming when proper forest management techniques aren't being used and resources are being cut sort of contributes to this phenomenon...doesn't it?

The pre existing dealers.

"Do you remember two advertisements you saw today?"

https://www.youtube.com/watch?v=x8iXj2vkpJI

You will remember at least one...

"not as the construct we have created to represent the wishes and needs of the people and society."

Does the government actually do that?

If you are asleep, can you hear it?