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Malarkey73

828 karma · joined January 23, 2014

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Malarkey73··on Brexit Is a Lehman Moment for European Banks
Hell will freeze over before the German government lets Deutsche Bank go bust.

They let Greece go bust rather than the Landesbank.

Malarkey73··on Britain’s vote to exit the EU sends Europe’s space sector scrambling for answers
Manufacturers will still abide by EU regulations. Otherwise their products won't be able to sell abroad.

The UK government just won't have any input - that's a REAL loss of sovereignty.

Malarkey73··on R Passes SAS in Scholarly Use
I'm not totally sure whether this analysis captures the true extent which R vs SAS vs SPSS is used.

If I use R for a plot, or a simple bit of regression, or anova, or even cross-validation. I don't reference it in a paper. I only cite it if there is a package designed for a particular type of data (e.g. a Bioconductor package) or something a bit more esoteric (e.g. apcluster). About 95% of the work is data munging and - sorry Hadley - I don't cite dplyr, purrr, magrittr etc...

However I have notice that in clinical trial or small social science papers simple analyses of this type are often cited as being done in SPSS or SAS. I think this just reflects the fact that non specialist data analysts are more likely to cite SAS or SPSS for simple procedures such as graphs or anova as an appeal to authority.

So I reckon the data may reflect a trend but tells us little about the true levels.

Malarkey73··on R Passes SAS in Scholarly Use
Yes and no - the dplyr example code heavily used pipes but that's really a feature of Magrittr package. You can used dplyr without pipes.

Plus dplyr essentially allows you to treat tables in a database as if they are data.frames.

Malarkey73··on Quitting your job to pursue your passion is a privilege
I also find these buzzwords annoying - but they're different. 'Privilege' is the only term from that list in the article...

'Trigger' I find annoying in almost every context; with the exception of facilities for the clinically traumatised I abhor the idea.

'Victim Blaming' is a useful term but I'm sure overused.

'Social Justice' seems more often these days sarcastically used as in 'Social Justice Warrior'

'Perpetuating false narratives' does seem just a pompous way of saying lies/propaganda.

... but returning to 'Privilege' I think that's a term that is overused - and annoyingly as in 'check your privilege' can be used to shut down a conversation or deny a viewpoint because of who someone is. A pernicious form of ad hominem.

And yet reading the article I think the argument is well made and the term 'privilege' is not used glibly. So perhaps it's unfair to write off the point just because that one word is used?

Malarkey73··on Facebook admits rogue employees may have shown bias against conservatives
Bayesian Star Wars : https://www.youtube.com/watch?v=l8IuGxP4Pa4
Malarkey73··on Machine Bias
I have this very concern about using SVM in medical research.

I also worry greatly about diagnostic predictive models that maximise overall prediction success but don't balance the relative consequences of false positives and false negatives.

Malarkey73··on Machine Bias
One of the most mind boggling sentences in that article was:

"On Sunday, Northpointe gave ProPublica the basics of its future-crime formula — which includes factors such as education levels, and whether a defendant has a job. It did not share the specific calculations, which it said are proprietary."

How on earth can you lock people up based on secret information? That is Kafka meets Minority Report.

Malarkey73··on The Real Lesson for Data Science That Is Demonstrated by Palantir's Struggles
A lot of this hit home to me as similar to my experience in bioinformatics - where all the formats are standardised and everything should be reproducible - but almost every project ends up completely different.

Software + Research = Chaos

Malarkey73··on If Philosophy Won’t Diversify, Let’s Call It What It Really Is
And forget Plato and ~half of Greek Philosophy.
Malarkey73··on Japan's Growing Poverty Defies Glib Explanations
Firstly the price of beans, CPUs and clothes may have fallen - but the price of education, healthcare, energy and especially housing have not fallen. They take up more and more of disposable income - and it's hard to argue that they are luxuries.

Second "when some people get a lot richer" this especially pushes up the cost of housing (arguably education too) a rationed good. The experience here in the UK is that more and more people are renting from those who have the money to corner the housing market. A vicious cycle of money being redistributed upwards.

No doubt type 1 and type 2 poverty are linked.

Malarkey73··on The 1% hide their money offshore, then use it to corrupt our democracy
That's wrong. The top 1% pay 30% of income tax. But this is only about a third of UK tax revenues. There is then NI, council taxes, property taxes, business taxes, VAT and duties.

The poorly paid actually spend a much higher % of there income in tax than the top 1%. And their contribution has been rising as the income and wealth based taxes are cut and the consumption based taxes have risen.

I don't blame you for thinking that is the case though as this canard has been pushed heavily by the UK press.

Malarkey73··on Playing “Moneyball” on EA FIFA 16
Having an objective measure of each players skills and their potential.

FIFA EA - Dribbling Ability: 23 (subjective)

Moneyball - On Base Percentage 23% (objective)

Malarkey73··on The Villain of CRISPR
There is a big difference between PCR and CRISPR though. Whilst PCR is effectively a reading technology, CRISPR is a writing technology. For many medical technologies then PCR is a standalone diagnostic tool (it is HUGE in mol. biol., pathology, biotech). However you can quite easily see CRISPR being a core tech within revolutionary deliverable medical treatments.

As Eisen points out its kind of odd that the group who rush to do the obvious human implementation should then get a share of all this potential... Not really a novel invention by that point in my opinion.

Malarkey73··on Google agrees to pay £130m in back taxes after an audit by UK tax authorities
This is an odd settlement though as it sort of ignores the law. Corporation tax is based on profits - which Google offshore to avoid UK tax (and many other places). Here they have said to them we see what you're doing - make nice. So they have drawn up a special formula (secret too) that pays a percentage of UK revenues - just for Google!

And of course whilst secret it leaves Google open to manipulate their UK sales too - as whilst they clam some Billions in their UK accounts in their US accounts they claim many Billions more.

With their now secret formula the UK public will never be able to pin them down when questioning what they are paying.

Malarkey73··on 'Snooper's charter' will cost British lives, MPs to be warned
Yes but with a complete DNA database you can match an external sample exactly to the database with (near) complete accuracy. The DNA database doesn't tell you anything itself.

With a database of all communications you have to mine it for probabilistic leads. The signal to noise problem grows as does the database.

Someone else (I cant recall who) said - the last thing you need when looking for a needle in a haystack is more hay.

Malarkey73··on Martin Shkreli Arrested on Securities Fraud Charges
If you can make exploitative profits from old drugs why risk your money making new ones?
Malarkey73··on Martin Shkreli Arrested on Securities Fraud Charges
Lets not forget too that Martin Shkreli took no risk inventing this drug. He bought a monopoly - a necessary lifesaving drug with no alternative - and jacked up the price by thousands.

Either a free market fundamentalist (ie no explotative patents) or a dyed in the wool regulator should be able to agree this is not how the market should work.

Malarkey73··on Europe’s Other Crisis: A Digital Recession
Yes the "digital evolution index" does sound a nebulous rag-tag list of stuff that the sponsors MasterCard and DataCash would like govermnets to implement or remove for them.

A complex issue no doubt - but I can't stand opinions dressed as "sciencey" research.

Malarkey73··on Lets All Go to Mars by John Lanchester
Book review and Comparison of The Wright Brothers by David McCullough with Elon Musk: How the Billionaire CEO of SpaceX and Tesla Is Shaping Our Future by Ashlee Vance
Malarkey73··on The Mighty Named Pipe
Vince Buffalo is author of the best book on bioinformatics: Bioinformatics Data Skills (O'Reilly). It's worth a read for learning unix/bash style data science of any flavour.

Or even if you think you know unix/bash and data there are new and unexpected snippets every few pages that surprise you.

Malarkey73··on Is 'SimCity' Homelessness a Bug or a Feature?
I don't think it is inane at all. Lots of games since Monopoly, Elite and running through Civilisation and SimCity have model economics, free trade, and free thinking ideas in-built into the game mechanics. And a lot of economics and free trade ideas seem to be justified by game theory and the naturalistic fallacy.

And a lot of chasing GDP or national wealth or Educational policy sometimes seem to be maximising some goal - like a game- rather than just running countries for the benefit of people.

I think its actually a very telling analogy if you think a little more deeply about it.

Malarkey73··on The Rise of Men Who Don’t Work – And What They Do Instead
[Objectively] in countries where a minimum wage has been introduced at a higher rate than the US and is reviewed each year it has pushed up wages but had little effect on employment.

e.g. see for instance this discussion http://www.economist.com/blogs/freeexchange/2013/02/labour-m...

Further I can't really stand the crocodile tears of business who want to employ workers at below living level wages. Their fake concern for worker is nauseating.

If workers are having to top up wages with food stamps and government aid then the business, management, and shareholders rather than the worker are effectively being subsidised by the taxpayer.

And if you let companies lower wages to compete then the bad employers drive out the good. Far better to make them compete on the product or service not how badly they are willing to treat people.

Malarkey73··on Space Tourism Isn’t Frivolous, or Impossible
Sorry is anyone who offers the contrary opinion - no matter how politely- that space tourism is frivolous, going to be voted down just because its an unpopular view about here?
Malarkey73··on To Get More Out of Science, Show the Rejected Research
Yes and No. Yes ecologists take more time to collect data.

However ecology is much cheaper than mol. biology. Essentially its ecology = manpower vs mol. biology = manpower + expensive technology + expensive chemistry.

Also ecology has been one of the most resistant fields to sharing data whereas genomics (the big data end of mol. biology) has been the most enthusiastic. There was a vey noticeable divide in opinion on twitter when PLOS journals mooted making authors make all their data public.

I think this is precisely because ecologists invest so much on collecting their field data, so they become possessive. Ecologists can become very senior PI by essentially owning a long term ecological study and assigning their students to continuing it.

Genomics and to a lesser extent Mol. Biol. has been keener recently to share as there is a strong open source ethos coming in from the computing side - and it is often a very expensive multi-centre, multi-agency collaboration.

Malarkey73··on Scottish Independence Referendum Data Map
Agreed. That's way off base. SNP voters won't make up half of the YES vote.

Its unpredictable as it's all down to how the Labour and previous non-voters fall.

Malarkey73··on The curious case of the cyclist’s unshaven legs
Its a very common phenomenon in science that a finding is published in a glamour journal e.g. Nature/Science and then if not immediately controversial e.g. acid bath stem cells, it becomes very difficult to publish something contradictory.

Journal referees will set the bar for such findings very very high...and you are quite likely to be refereed by the original author or their friends.

I know this to my cost having gone to extraordinary lengths to publish something slightly contradictory in a far lower impact journal than the work deserved.

Malarkey73··on A surge of p-values between 0.040 and 0.049 in recent decades [pdf]
The idea that you get a lot of just marginal significant results due to "P hacking" , i.e. minor fiddling with excluding outliers or picking a certain hypothesis test over another is probably true. Then there is positive publication bias i.e. only publishing positive findings.

However looking in the abstract doesn't really address either of these .. as even absent either P hacking or positive bias you would still expect the abstract to contain the selected highlights (i.e. positive findings) from the paper. It is the bit of the paper where you really should have positive selection bias!

If the paper has lots of negative tests (and most biological papers will report lots of negative control p values) these aren't picked up. A better way to see this problem (and I believe it is a problem) is to look at the whole paper and view the peak of margin results) compared to the whole set of p values.

Malarkey73··on A $650M Donation for Psychiatric Research
I don't think for psychiatric research we should start with the presumption the end goal is necessarily "drugs on the shelf".

it might or might not be a good goal for some conditions.

Malarkey73··on Amazon snubs French free delivery ban with one-cent charge
They are exceptionally poorly paid and insecure. Here in the UK most of them are on benefits. Effectively my taxes are subsidising their profits.
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