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NobleLie

52 karma · joined January 24, 2015

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NobleLie··on Language models can explain neurons in language models
A mirror of ourselves*
NobleLie··on Significant breakthrough in search for Parkinson's biomarker
Imagine symptoms improving being in the placebo group?

What are the statistics on that?

NobleLie··on Trashcan – web based service for indexing scientific papers, or other documents
I believe you are asking OP?

If you were asking me, this software is very minimal and not going to compete with zotero for an unknown time frame. What's your current need after using zotero? (Just curious)

---

That being said, I really appreciate these initiatives and applaud author of this library, didn't confirm but probably a one-person team.

NobleLie··on ChatGPT 4 saved my dog’s life
Better than the average human professional...at taking tests.

Not better at being a useful doctor able to intake a patient and get to the bottom of an unspecified disease. Both doctors and AI are generally poor at doctoring. Only a small fraction of doctors are good at being doctors. No LLM is good at being a doctor.

NobleLie··on Generative AI is overrated, long live old-school AI
Spoken word into microphone implementation:

Run run control with speed argument 100.

AI: "Scheduling you for a speech therapist session to work on your stutter"

NobleLie··on Toxic air pollutants in E. Palestine could pose long-term risks, researchers say
Well I did claim he should know that. Maybe he does, maybe he doesn't. If he does, that jumps this ship into conspiracy territory (conspiring to belittle those concerned, without evidence) and he doesn't, he should be immediately released from his position due to mental inadequacy (it's bordering common sense)

I've heard far dumber things said and no culpability so I imagine nothing to change.

NobleLie··on Toxic air pollutants in E. Palestine could pose long-term risks, researchers say
Wow.

I think the last non negligible accident including vinyl chloride was 2012, and it was ~6x less bulk volume than this one (20k gallons as opposed to 120k)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776704/

And it wasn't managed via a controlled burn.

Buttegieg should know that it's not about the number of derailments but the chemicals involved, the volume / mass involved, the conditions of leakage / spillage, environmental spread and finally the chosen response to mmmanage (which sometimes can make the problem worse or trade one problem for another)

NobleLie··on Ask HN: Why pay for ChatGPT premium instead of using GPT3 playground?
ChatGPT, what is the best way to cook an egg?

"Before I dive into answering your question, let me take a quick moment to advertise a completely unrelated product. Have you ever found yourself in the middle of an intense workout, only to realize that your gym clothes are too baggy, too tight, or too uncomfortable? Say no more! Introducing the FlexFit Pro 2000, the ultimate workout gear for fitness enthusiasts. With its state-of-the-art fabric and ergonomic design, the FlexFit Pro 2000 will keep you cool, dry, and comfortable, no matter how hard you train. And the best part? It comes in three exciting colors: black, dark black, and slightly less black. Don't wait, order now and take your workouts to the next level!

Now, to answer your question: There are a lot of different opinions on the best way to cook an egg, but ultimately it comes down to personal preference. Some people like their eggs fried, while others prefer them scrambled or boiled. Regardless of how you choose to cook your eggs, it's important to make sure they're cooked thoroughly to reduce the risk of foodborne illness."

I asked it to do this, and removed it from the query lol

NobleLie··on Reddit is experiencing a partial outage
"Let me run the reverse reverse migration script again"
NobleLie··on The case for hanging out
The manufactured new normal. I feel you, anon.
NobleLie··on The rise and fall of Microsoft’s new Bing
Where did you learn that the brain works by simply predicting the next most likely word in a sentence?

Tertiary note: I'm also a programmer and a researcher. It's failed pretty hard on both. Faking sources of medical / biological information, botching simple chronology, suggesting made up methods on well known programing libraries (3 of many examples). There was nothing I could do to correct any of these errors - no matter how much leading or pointing out error, it would acknowledge it and repeat it.

I recognize the value of chatgpt (and roughly how it operates) but the excitement (marketing hype) is indeed over the top. It appears an incremental advancement of old word2vec (added human supervision and a few more things) but the sum total is still of questionable value in domains that mean the most to me (admittedly self centric, but many are like me, at least here)

NobleLie··on Why does the SARS-Cov2 genome end in aaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa? (2020)
I don't think the genome has a specific length of the tail (33 is a consensus length)

During genomic assays, the poly a tail will not be a specific length, but a single consensus sequence is still provided.

This was also posted in the first comment:

> Similar to eukaryotic mRNA, the positive-strand coronavirus genome of ~30 kilobases is 5’-capped and 3’-polyadenylated. It has been demonstrated that the length of the coronaviral poly(A) tail is not static but regulated during infection; however, little is known regarding the factors involved in coronaviral polyadenylation and its regulation. Here, we show that during infection, the level of coronavirus poly(A) tail lengthening depends on the initial length upon infection and that the minimum length to initiate lengthening may lie between 5 and 9 nucleotides. By mutagenesis analysis, it was found that (i) the hexamer AGUAAA and poly(A) tail are two important elements responsible for synthesis of the coronavirus poly(A) tail and may function in concert to accomplish polyadenylation and (ii) the function of the hexamer AGUAAA in coronaviral polyadenylation is position dependent. Based on these findings, we propose a process for how the coronaviral poly(A) tail is synthesized and undergoes variation. Our results provide the first genetic evidence to gain insight into coronaviral polyadenylation.

Peng Y-H, Lin C-H, Lin C-N, Lo C-Y, Tsai T-L, Wu H-Y (2016) Characterization of the Role of Hexamer AGUAAA and Poly(A) Tail in Coronavirus Polyadenylation. PLoS ONE 11(10): e0165077

NobleLie··on Ask HN: Is anyone else getting AI fatigue?
Agreed. Been testing out responses to parsing complex genomics papers (say, a methodology section describing parameters of some algorithm) and its mostly rephrasing rather than digesting and responding with useful information / interpretation. And it will use so many words and imbue so little to the conversation, yet appear like it's helping because ... words.
NobleLie··on Ask HN: Is anyone else getting AI fatigue?
Source for consciousness / intelligence to be "statistics"?

I don't think there is any because there is no functional model for what organic intelligence is or how it operates. There are plethora of fascinating attempts / models but only a subset implore that it is solely "statistical". And even if it was statistical, the implementation of the wet system is absolutely not like a gigantic list of vectorized (stripped of their essence) tokens

NobleLie··on The Future of the Word Processor (2016)
Digital becomes a real boon when you are creating knowledge networks; connecting pieces of information, or tagging them. This metadata is, as far as im aware, best suited for being stored digitally.

Disclaimer: I'm working on a knowledge management app thats core focus is connections and tagging (amongst many other useful features)

NobleLie··on What Do Animals See in a Mirror? (2014)
Well, the reaction of a frightened cat isnt, by design, one that appears friendly. They usually jump and get a puffy tail. If the cat observes his reflection jumping and getting a puffy tail, itd make sense for the cat to assume danger, for he just ran into another cat whom got freaked out seeing him.

That is, if the cat doesnt recognize itself rather quickly

NobleLie··on Don’t Take My Folders Away: Organizing Personal Info to Get Things Done (2005)
My point was that in gmail, tags dont inherit their parent when searching

Example:

  - Action
    - Task
       - Closed
       - Open
When searching action, its my preference to see all items tagged with either Action, Task, Open or Closed, but gmail only filters for Action
NobleLie··on Don’t Take My Folders Away: Organizing Personal Info to Get Things Done (2005)
See my sibling post :-)
NobleLie··on Don’t Take My Folders Away: Organizing Personal Info to Get Things Done (2005)
Hi. My brother and I are working on a note taking system; one of the focuses being increased utility of tags.

Of note relating to tags:

- tags are hierarchically organized and inherit their parents. (Systems like gmail and evernote dont do this?! o_O)

- NOT and AND blocks

- Option for seeing full lineage of tag

- "Tag Clusters" which are basically a named group of tags that are commonly used and can be bulk applied to an item

On the way: Full AST (abstract syntax tree) tag/user/text querying (the UI isnt the easiest to nail down for OR / parenthetical groups)

Laddice.com (desktop app only right now)

Feel free to check it out, make an account and email me with thoughts, opinions and/or requests (email's in my profile.)

Would love to talk more about this with you!

NobleLie··on Why Do DMT Users See Insects from a Parallel Universe?
Magical Thinking, eh?

Vaccines and the entire concept of hormesis is something you should research when you get the chance.

NobleLie··on Why Do DMT Users See Insects from a Parallel Universe?
Look into Ouroborous, Jungian Archetypes, and Kekules notes on his dreams.

Crazy world we live in...

NobleLie··on The Purpose of Sleep? To Forget, Scientists Say
> lack of inertia.

What? No, im pretty sure that some people knew what friction was and that if theoretically, there was none of it, things would continue to move. Thats intuitive to me.

> Spontaneous generation of animals.

Fair example; ive read this old theory before.

> Leeches Blood letting is still somehow advised as being healthy for certain conditions (too much iron, and "resetting" a percentage of ones blood. That or they just really want people to donate) Plus you even admit that youre not sure about it being 'false' fact brought by intuition, so why even include that?

OP's point is not that intuition is infallible. Not much is infallible (perhaps nothing, if one is atheistic) It's that science has seemed to shunt/reduce/eliminate the intuition of a subsection of the population. It's his opinion (and mine) that this has harmful effects that are worth examining.

NobleLie··on Psychiatrists Must Face Possibility That Medications Hurt More Than They Help
Is this "30% deficit" (citation needed) conquerable by training and meditation?
NobleLie··on How to grow into your best developer self
His whole point is that reading comments first is the mistake. It primes you with thoughts and opinions with little to no cognition required (recognizing they still may be valuable, but those comments will be there after your analysis...)

What we really need is to develop our own critical reading skills, how to connect dots on our own etc. I agree that seeing others comments first before starting that process might be a negative for many reasons.

NobleLie··on You Are Not Paid to Write Code
> I think the thing that convinced me was when I got to start watching lots of technology teams in the wild across multiple organizations. So many times I would see conversations and tons of problem-solving effort being spent on the tools to solve the problem instead of the problem itself

Your insight really hit home. Especially since I've been on a new software dev position for about a month now. This is the overwhelming issue that is already reared its ugly head, is massively frustrating and I feel (nearly) powerless to stop it.

NobleLie··on Ask HN: Have you ever thought of leaving programming for something else?
Would you mind explaining what you mean by targeted individual? Did you do something to attract someones attention in a really negative way? How did this come about through programming?
NobleLie··on Should you give up on your dream? Here's how to know.
Sound article. Im also a musician/sing writer/web app developer =)

I really like your personal promotion site for development. But I extremely dislike the centered text in all the modals (at least thats how it is on my phone)

Any reason you did that? Makes reading at least twice as difficult.

Still a very nicely done site just felt the need to let you know this.

Oh and if youre curious, just released this today! https://www.soundcloud.com/nobalai/ghosts-in-my-head-ft-sine...

NobleLie··on Bullet journal: A simple productivity system that just uses pen and paper
How do you remember what you failed to remember?

How do you even evaluate your memory if youve never catalogued your thoughts for a few years (or less or more) ?

NobleLie··on A New Theory of How Consciousness Evolved
Because it's a possibility that consciousness is not merely observable actions or even internal thoughts (the "output")... but the feelings which guide/cause those actions (where feelings are not defined as an algorithm or computation)

So even if a robot and human had the same input-outmap mapping, one could be "coded" by "consciousness", the other by whatever humans invent as an algorithm. Maybe they will be identical, maybe they wont be. Im certainly not sure.

NobleLie··on A New Theory of How Consciousness Evolved
Your example makes sense. But your last paragraph is precisely why its grasping with the most simple and largest of solutions. Id expect the consciousness simulating robot to contain such a fact generator, not some brute force word combiner algorithm. In other words, it'd have a knowledge/concept/argument/etc network.

I recognize the grandparent poster mentioned something about having enough if statements, but yea, thats not how its going to work.

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