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Octokiddie

2,449 karma · joined November 27, 2022

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Octokiddie··on Nobel Prize in Medicine awarded to Katalin Karikó and Drew Weissman
Title ("Price") is misspelled.
Octokiddie··on The United States of Bed Bath & Beyond
The premise of the piece depends on making a connection between BBY and the US. I'm not sure it works.

> In the American context, my personal view is that Bill Clinton and George W. Bush presided over Bust Out 1, Barack Obama orchestrated Bust Out 2, and Donald Trump kicked off the lulz period, which we are now squarely in. I mean, how can you understand Trump and Biden as anything other than lulz?

Those BBY bust-outs were its leadership sucking the company dry. How did Clinton, Bush, Obama, and Trump suck the country dry? I'm not saying those leaders were effective but rather asking the more specific question about the connection between those administrations and the BBY serial vampire syndrome. The article seems to be saying that wealth/vitality was somehow sucked from the US into the leaders themselves or their cronies. If so, name names. Or at least offer a single example.

Instead, the article ends up with a much less interesting message. The US is going down the tubes and has been for a long time. That's a very old idea that may go back to the country's founding. It doesn't offer new insights. It doesn't open new perspectives. It just riles people up for a time. It's the kind of thing that politicians looking for new slogans to congeal a base of support turn to in campaign speeches so they can portray themselves as the only one who can drain the swamp.

Octokiddie··on Ken Follett Says Readers Still Like Epic Books
The article doesn't define "Epic Book." Is it just a really long book? Is there something more to it? How many pages is the cutoff?
Octokiddie··on One in 10 Japanese Now Aged over 80, Population Report Shows
> Japan’s steps to bolster the birthrate haven’t been successful, while authorities have been hesitant to accept large numbers of migrant workers to make up the shortfall.

It's hard to imagine how Japan can keep on the current path. But it's also hard to imagine how they'd adapt to normalized immigration. Seems like an adapt-or-die situation.

Octokiddie··on The brain is not an onion with a tiny reptile inside (2020)
> Does it matter if psychologists have an incorrect understanding of neural evolution? One answer to this question is simple: We are scientists. We are supposed to care about true states of the world even in the absence of practical consequences. If psychologists have an incorrect understanding of neural evolution, they should be motivated to correct the misconception even if this incorrect belief does not impact their research programs.

The hallmark of an incorrect model in science is that it makes incorrect predictions about the natural world (experiment). What incorrect predictions has psychology made based on the incorrect triune-brain theory?

I'm going to guess zero, not because the model works, but because psychology has made no experimentally testable predictions based on it.

Octokiddie··on 'Atomic Energy' Book Signed by Einstein, Oppenheimer, Bohr, Enola Gay Crew
The title fits into a broad pattern of misdirected attention about atomic weapons. The cover story is always "energy" but the underlying truth is all about weapons. It's the same for every country, too, it seems.
Octokiddie··on Ask HN: Tech that seems to have vanished?
Physical newspapers and books. Not trying to be cute, but it's very easy for these vanishing technologies to, well, vanish.
Octokiddie··on New JFK assassination revelation could upend the lone gunman theory
Cutting to the chase:

> He claims he spotted a bullet resting on the top of the back of the seat. He says he picked it up, put it in his pocket, and brought it into the hospital. Then, upon entering Trauma Room No. 1 (at that stage, he was the only nonmedical person in the room besides Mrs. Kennedy, and both stayed for only a short period), he insists, he placed the bullet on a white cotton blanket on the president’s stretcher.

> ...

> Yet the bullet that Landis now claims to have discovered that morning emerged largely intact and only moderately damaged, its base having been squeezed in.

Octokiddie··on Every aspiring writer should read terrible books (2022) [video]
Has anyone ever written a book on what makes bad writing?
Octokiddie··on Toyota blames factory shutdown in Japan on ‘insufficient disk space’
Can anyone offer evidence that this is not due to low demand, with insufficient disk space being used as an excuse?
Octokiddie··on The worst programmer I know
What's the metric for programmers who prevent the team from building the wrong product?
Octokiddie··on Taking dietary supplements full of antioxidants could help cancerous tumors grow
The original study reports only in vitro data. Call me skeptical about the sweeping conclusion in the title.

https://www.jci.org/articles/view/169671

Octokiddie··on West Point discovers time capsule from 1828
> The capsule was found in 2023 when the monument's base was removed from the site.

This is a reminder of how quickly things are forgotten. In this case, the presence of the time capsule was forgotten within the span of less than 200 years. I suppose those who placed the capsule could have done so under complete secrecy. More likely a few people knew about it, but that knowledge just disappeared with those who knew it.

Octokiddie··on AC/DC's Thunderstruck on Tesla coils [video]
The guy in the background looks fake.
Octokiddie··on Oral cancer drug kills 100% of tumors in vitro and in animal models
It seems to be getting more popular here to link to a twitter blurb, which links to the actual article. In this case, the blurb adds zero to the discussion, if anything adding blatant misinformation.

This is the actual article:

https://www.cell.com/cell-chemical-biology/pdfExtended/S2451...

I recommend replacing the link and the title with what appears on the Cell website.

Octokiddie··on Bark beetles are eating through Germany’s Harz forest
> But the tiny insects have been causing outsized devastation to the forests in recent years, with officials grappling to get the pests under control before the spruce population is entirely decimated. Two-thirds of the spruce in the region have already been destroyed, said Alexander Ahrenhold from the Lower Saxony state forestry office, and as human-caused climate change makes the region drier and the trees more favorable homes for the beetles’ larvae, forest conservationists are preparing for the worst.

It seems this is not exactly new:

> Around 1800, large swathes of the Harz were deforested. The less resistant spruce monoculture, that arose as a consequence of the mining industry in the Upper Harz, was largely destroyed by a bark beetle outbreak and a storm of hurricane proportions in November 1800. This largest known bark beetle infestation in the Harz was known as the Große Wurmtrocknis, and destroyed about 30,000 hectares (74,000 acres) of spruce forest and lasted about for 20 years. The woods were largely reforested with spruce. Continuous problems with bark beetle and storms were the negative side effects of mining in the Harz Mountains.

https://en.wikipedia.org/wiki/Harz

> In the longer term, mixing other tree species into the forest could be a solution, Ahrenhold said. “It makes sense to plant other conifers that can cope better with these conditions, especially on south-facing slopes and on very dry soil,” he said.

The AP article fails to mention the massive amount of deforestation and animal depopulation that's occurred for centuries now, but which is well-documented in the Wikipedia article. This gives the misleading impression that what's happening now is somehow unprecedented.

The issue, it seems, is that trying to "manage" the land doesn't work. It may even be more the root of the problem than the solution.

Octokiddie··on Winter temperatures above 35C in South America leave climatologists in disbelief
The alarmist tone of this article inspires zero confidence in the reporting. For example:

> Climatologist and weather historian Maximiliano Herrera went so far as to call it [35 C+ temperatures in winter] one of the most "extreme weather events the world has ever seen".

Assuming the quote is not taken out of context and Herrera did say it, I'm not sure the facts are on Herrera's side. The world likely saw more extreme "weather events," such as the one that happened at the end of the Pleistocene. That's when the half-mile-thick layer of ice sitting over the northeastern part of North America melted to expose the land beneath.

Octokiddie··on Cut out everything that's not surprising (2019)
Oddly, the author doesn't follow their own advice. Nor do they support the claim on which the entire article depends:

> People only really learn when they’re surprised.

The idea that people learn when surprised is not surprising. The idea that people only learn when surprised could be surprising, but only if substantiated. I would be surprised because I can think of numerous times that I learned when not surprised.

Surprise is fine as a technique to draw the reader in, but it puts you on the hook to support the surprising claim. And the act of whittling that claim down to something supportable could very well leave you with nothing very surprising at all.

Octokiddie··on Huazhong University demonstrates LK-99 diamagnetism
The tweet does not link to a paper reporting a "replication," but rather two theoretical papers. The title is therefore misleading.
Octokiddie··on The Pacific Northwest Tree Octopus
> The reasons for this dire situation include: decimation of habitat by logging and suburban encroachment; building of roads that cut off access to the water which it needs for spawning; predation by foreign species such as house cats; and booming populations of its natural predators, including the bald eagle and *sasquatch*.

I feel like I should have figured out this was a gag sooner...

Octokiddie··on Elon Musk says Twitter’s ad revenue is down 50% and cash flow is negative
> “It’s definitely been extremely difficult,” Musk said in Twitter Spaces livestream event Musk hosted with Robert F. Kennedy, Jr last month. “Basically, our revenue is cut in half because we didn’t toe the line.” He added it’s been a “huge struggle for Twitter to break even.”

Toe what line?

Octokiddie··on A third of North America’s birds have vanished
It's surprising to see so many comments here jumping to the conclusion that the article is pointing the finger at carbon emissions. It's not. The article doesn't credit any single cause with the drop. Nor does it spin any solutions.

It does note a correlation, and from that a possible cause. And there, the link between observation and putative cause is not supported:

> The hardest hit were grassland birds, down by more than 50 percent, mostly due to the expansion of farms that turn a varied landscape into acres of neat, plowed rows

The article mainly reports a numerical finding.

Octokiddie··on Harvard professor Avi Loeb believes he's found fragments of alien technology
> "We found ten spherules. These are almost perfect spheres, or metallic marbles. When you look at them through a microscope, they look very distinct from the background," explained Loeb, "They have colors of gold, blue, brown, and some of them resemble a miniature of the Earth."

> An analysis of the composition showed that the spherules are made of 84% iron, 8% silicon, 4% magnesium, and 2% titanium, plus trace elements. They are sub-millimeter in size. The crew found 50 of them in total.

Everything in the description could have been produced on Earth using existing technology.

Isotopic composition of the metals could be a very simple way to differentiate the terrestrial from the alien. It's an easy analysis to perform. The fact that it isn't reported at all suggests that Avi Loeb may not have the extraordinary evidence to back up the extraordinary claim.

Octokiddie··on Aspartame: Once More Unto the Breach
At face value, it's far from clear how this molecule was discovered. Nothing about the structure indicates that it would taste sweet. Wikipedia offers this account:

> Aspartame was discovered in 1965 by James M. Schlatter, a chemist working for G.D. Searle & Company. Schlatter had synthesized aspartame as an intermediate step in generating a tetrapeptide of the hormone gastrin, for use in assessing an anti-ulcer drug candidate. He discovered its sweet taste when he licked his finger, which had become contaminated with aspartame, to lift up a piece of paper.

https://en.wikipedia.org/wiki/Aspartame

But the Washington Post seems to disagree:

> It has been 17 years since chemist James M. Schlatter, who was tinkering with an anti-ulcer drug at the time, dipped his finger into a mixture of asparatic acid and phenylalanine and, for reasons that remain unclear, brought the result into contact with his tongue. Now, after a long legal and scientific struggle, the stuff that was on Schlatter's finger that fateful day in 1965 can be on your finger too, or dissolved in your coffee, or stirred into your yogurt, or sprinkled over your cinnamon toast.

https://www.washingtonpost.com/archive/lifestyle/food/1982/0...

There was a time when reporting the taste of a newly-synthesized organic molecule was not uncommon in the literature. It's possible that Schlatter was just doing something that was not unusual at the time.

An account of the discovery, written by one of the authors of the original research paper reporting the discovery (Mazur), and reportedly based on an affidavit gives this account:

> In December 1965 I was working with Dr. Mazur on the synthesis of the C-terminal tetrapeptide of gastrin. We were making intermediates and trying to purify them. In particular, on an occasion in December, 1965, I was recrystallizing aspartylphenylalanine methyl ester (aspartame) ... when the mixture bumped [spilled over while boiling] onto the outside of the flask. As a result, some of the powder got onto my fingers. At a slightly later stage, when licking my finger to pick up a piece of paper, I noticed a very strong, sweet taste. Initially, I thought that I mush have still had some sugar o. my hands from earlier in the day. However, I quickly realized this could not be so, since I had washed my hands in the meantime. I, therefore, traced the power on my hands back to the container into which I had placed the crystallized apsartyl-phenylalanine methyl ester. I felt that this ... was not likely to be toxic and I therefore tasted a little of it and found that it was the substance which I had previously tasted on my finger.

- Aspartame: Physiology and Biochemistry, edited by Stegink and Filer

Octokiddie··on How to Do Great Work
> What are you excessively curious about — curious to a degree that would bore most other people? That's what you're looking for.

This is a great article, but there are many, many people for whom this advice is going to lead nowhere or worse. They have often been to fancy universities and have often earned fancy degrees. But what they don't realize is that they've also been trained to respond to the praise of authority figures. The article touches on this point later, but emphasizes a different outcome.

If there's one thing that authority figures absolutely hate is a project that makes you excessively curious.

I'll speculate that those most affected by this perverse reward system will deny its influence over them most strongly. They won't realize that their motivation for projects stems from the enthusiasm that authority figure show or withhold. They will therefore conclude that the warning above does not apply to them. And they will have a very hard time.

I saw this first-hand in graduate school. At least half the students had never learned to disregard the level of the greybeard's enthusiasm when choosing projects. Unsurprisingly, they also did not understood the process of formulating a project idea. This was the half that had, by far, the hardest time. At the slightest hint of graybeard apathy for a project idea, they were onto something else.

Octokiddie··on In deep space, astronomers spot precursor of carbon based life
The article is misleading, making it seem as if methyl cation, the species observed, were an essential component of life. It's not.

> Astronomers wielding the James Webb Space Telescope have detected methyl cations – important precursor molecules needed to create proteins and DNA and therefore fundamental to carbon-based life forms.

No study to date spells out a plausible path to abiogenesis - the creation of life from non-living chemical precursors. Without such a path, claims that any particular molecule is a "precursor of carbon based life" are suspect at best.

Octokiddie··on Eating microwave popcorn increases the level of PFAS in body (2022)
> A study published in 2019 analyzed a decade of data about the eating habits of 10,000 people, which was collected by the Centers for Disease Control and Prevention between 2003 and 2014. Blood samples from the study participants were also collected. The researchers found that people who ate microwave popcorn every day over the course of a year had levels of PFAS that were up to 63% higher than average.

1. Is it too much to ask for a link to the original research in an article like this?

2. Given that every human alive has detectable levels of PFAS in blood, 63% elevation after eating every single day of the year doesn't seem like a lot.

3. Those advocating popping in pans/pots might want to consider what that pan/pot is coated with.

Octokiddie··on Typography 2024: For America’s Best
Clicked on Kennedy's website because the screenshot looked like he was winking on the homepage. I wanted to check. He's not, but there's no https, which breaks the link used in the article.
Octokiddie··on Benzene Exposure Alters Endocrine Activity
Benzene's wide-ranging negative health effects have been known for a long time. It's far from clear why this article reporting the results of a mouse study with rather unremarkable findings is on the front page.
Octokiddie··on US urged to reveal UFO evidence after claim that it has intact alien vehicles
Zero specific claims. Zero evidence examined by the person making the allegations. All hearsay.

To top it off, the focus of the story, David Charles Grusch, is a "a former intelligence official."

Pardom me for disregarding this as the diversion it appears to be. The US military has quite a track record on this kind of thing. It's not hard to think of reasons why such diversions might be deployed right now, either.

Maybe some kind of physical evidence - any physical evidence - will be presented. If so, I'm happy to change my mind. Until then, there's zero compelling reason to believe any of it and every reason to think Grusch either a liar or a stooge.

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