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PudgePacket

1,331 karma · joined July 31, 2014

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PudgePacket··on Rust 1.45
Rust also statically links by default.
PudgePacket··on Pinephone – “Community Edition: PostmarketOS” Linux smartphone
Could PWA's be installed on a phone like this, through browsers like chrome or firefox? That would greatly lower the barrier to entry to "develop" for them!
PudgePacket··on Can an extreme low carb diet be used as medicine?
1. People on western diets. This isn't some hidden mystery.. it's in plain view. Plenty of studies done, or just ask _any_ doctor that sees patients, or any of your friends/family who have tried diets. Or search pubmed for diet adherence.

2. Because their base metabolic rate reduces over time to match their new reduced caloric intake.

PudgePacket··on Can an extreme low carb diet be used as medicine?
Your body makes more cholesterol than you get from diet, it's more complicated than just "cholesterol high = bad".

Also would encourage you to read up on recent literature about fats. The "low fat = healthy" fad hasn't held up for some time.

https://www.sciencedirect.com/science/article/pii/S073510972...

> The recommendation to limit dietary saturated fatty acid (SFA) intake has persisted despite mounting evidence to the contrary. Most recent meta-analyses of randomized trials and observational studies found no beneficial effects of reducing SFA intake on cardiovascular disease (CVD) and total mortality, and instead found protective effects against stroke.

PudgePacket··on Can an extreme low carb diet be used as medicine?
Humans can produce all the glucose they need when in nutritional ketosis or starvation ketosis.

https://en.wikipedia.org/wiki/Gluconeogenesis

PudgePacket··on Can an extreme low carb diet be used as medicine?
> We're optimized for eating lots of sugar.

Not even sure how to respond to that one. American diabetes rates?

> Primates have a hard time producing fat from carbs

??? carbs -> glucose -> insulin -> increased lipogenesis. Carbs are _better_ than protein or fat at producing bodyfat.

> Is eating lots of animal products bad for you? Yes. It's been shown again and again in large studies that humans do better on predominantly whole plant foods.

In large, observational studies with innumerable co-founding factors, including lumping regular meat (a steak) in with highly processed meat (mcdonalds burger).

I agree with the whole food part, and plants can be good, but exclusion of unprocessed meat is not proven to be any more healthy.

You also self describe as vegetarian in your profile, and ketogenic diets often include meat.

PudgePacket··on Can an extreme low carb diet be used as medicine?
> https://pubmed.ncbi.nlm.nih.gov/23273808/

> Conclusions: The KD is a safe and efficacious therapy for intractable childhood epilepsy in Chinese children. The influence of age on efficacy is worth further investigation.

?

PudgePacket··on Can an extreme low carb diet be used as medicine?
Firstly those studies are all in children..

Study 1 doesn't actually show increases in kidney stones.

Study 2 has N of 4...

Study 3 looks reasonable, though they did note "use of oral potassium citrate significantly decreased the prevalence of stones" which is good news!

Study 4 has N of 25 & no info about what they actually ate other than macronutrient ratio.

PudgePacket··on Can an extreme low carb diet be used as medicine?
Yes yes calorie in calorie out blah blah. Most people can't maintain a caloric deficit for an extended duration. Countless studies have shown that.

The point is people who are overweight tend to lose weight when eating ad libitum on a ketogenic diet, whereas people on a standard diet generally gain weight (see western populations).

PudgePacket··on Linux kernel in-tree Rust support
Slightly off topic, I see D brought up incredibly consistently when Rust is mentioned on HN.. Is it just me?? (it's usually by walter themself but I digress..)
PudgePacket··on Tesla’s SA big battery just got 50% bigger after goals thanks to Autobidder
SA = South Australia for the rest of the world.
PudgePacket··on Algolia introduces pay-as-you-go pricing for search
1 MB * 1,000,000 = 1 TB
PudgePacket··on The Sci-Hub Effect: Sci-Hub downloads lead to more article citations
https://en.wikipedia.org/wiki/FUTON_bias

> FUTON bias (acronym for "full text on the Net")[1] is a tendency of scholars to cite academic journals with open access—that is, journals that make their full text available on the Internet without charge—in preference to toll-access publications.

PudgePacket··on WebTransport API
Not sure if you missed it or not but QUIC is HTTP3. It has known advantages that are highly valued in domains like games as josephg has mentioned.
PudgePacket··on Foam – A Roam Research alternative with VSCode, Markdown and GitHub
I have syncthing running on desktop, laptop, and phone. Only downside is no iOS app but that's more an apple ecosystem issue really.
PudgePacket··on Blackballed by PayPal, Sci-Hub switches to Bitcoin
Just because you have an ideological belief doesn't mean you're somehow magically exempt from participating in the currently capitalist world. People still need to purchase food, pay bills etc.
PudgePacket··on Safari now blocks Google Analytics on sites, new Privacy Report feature shows
Not saying there isn't value in Apple brand, or that it's bigger, just that DDG's value is in it's brand.
PudgePacket··on Safari now blocks Google Analytics on sites, new Privacy Report feature shows
Not saying there isn't value in Apple brand, just that DDG's value is in it's brand.
PudgePacket··on Facial Recognition Leads To False Arrest Of Black Man In Detroit
Sure.. But the case being discussed has a maximum frequency of 1 in a million every 18 (2 terms of childbirth) months, further reduced by needing to be a woman of reproductive age, fertile, etc etc.

This case of "one in a million" does not happen frequently.

PudgePacket··on An experiment suggested by a PhD student may rewrite chemistry textbooks
Reminds me of Dr. Banting and the isolation/discovery of insulin, ultimately leading to a nobel prize.

> Banting was no expert in the field of carbohydrate metabolism, so when he requested laboratory space and facilities from Professor John James Rickard Macleod, Head of Physiology at the University of Toronto, the esteemed physiologist was at first reluctant.

> However, Banting’s persistence and the possibility of more reliable results persuaded MacLeod to donate laboratory space. While tying up the pancreas to make it break down was not a new investigative tool, the idea of isolating islets due to their slower degeneration was of keen interest to Macleod.

https://www.medicalnewstoday.com/articles/323774#development

PudgePacket··on Safari now blocks Google Analytics on sites, new Privacy Report feature shows
The value in DDG is the userbase and brand.
PudgePacket··on Booting embedded Linux in 0.37 seconds on an ARMv7-A CPU at 528 MHz
Is it pulling a fresh docker image each time?
PudgePacket··on Rav1e, an AV1 encoder written in Rust and assembly
> safer

For any reasonable definition of "safer", yes. 100% safe? no.

PudgePacket··on Storage Matters: Why Xbox and Playstation SSDs Usher in a New Era of Gaming
This was actually a really awesome presentation. I don't think the intended audience was their customers, perhaps more for the media & gamedevs.
PudgePacket··on Study of the effect of Vitamin D, Magnesium and Vitamin B12 on Covid-19 patients
Looks like it was larger than I thought!

https://pubmed.ncbi.nlm.nih.gov/30611908/

> In summary, long-term supplementation with vitamin D3 in doses ranging from 5000 to 50,000 IUs/day appears to be safe.

https://www.mayoclinicproceedings.org/article/S0025-6196(15)...

> The evidence is clear that vitamin D toxicity is one of the rarest medical conditions and is typically due to intentional or inadvertent intake of extremely high doses of vitamin D (usually in the range of>50,000-100,000 IU/d for months to years).

You can find more sources by scrolling down to the "summary" section, https://www.foundmyfitness.com/episodes/jre-1474

PudgePacket··on Study of the effect of Vitamin D, Magnesium and Vitamin B12 on Covid-19 patients
Everything is toxic in unsuitable amounts, it's an empty statement that doesn't really serve any purpose and is impossible to discuss.
PudgePacket··on Study of the effect of Vitamin D, Magnesium and Vitamin B12 on Covid-19 patients
> Patients were administered oral vitamin D3 1000 IU OD

I've seen multiple sources say that 1000 IU of vit D is usually insufficient to boost levels, with suggestions of up to 5000 a day. My mothers doctor put her up to 2000 a day because 1000 did nothing to her levels, which were already low.

PudgePacket··on A simple way to get more value from tracing
?
PudgePacket··on Show HN: Unity MMORPG Boilerplate – Multiplayer in Unity Made Easy
Try GameMaker or Construct. They are the more intro level tools that will let you get things done without having to learn too much.

After there is the big engines, Unity, Unreal, and Godot. They all have their ups and downs, but are the next level of complexity up from the previously mentioned tools.

If you're into specific niches there are sometimes purpose built engines for it, like RPG Maker. They are usually much less complex, albeit limited to specific kinds of games.

PudgePacket··on Show HN: Unity MMORPG Boilerplate – Multiplayer in Unity Made Easy
> * Pulling updates from the GitHub releases page will probably get your repository rate-limited if not taken down, you need to think carefully about how to scale that up.

This is the default mechanism for electron apps to auto update, and I haven't heard any issues from it to do with rate limiting.

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