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addisonl

384 karma · joined May 10, 2019

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addisonl··on An SR-71 Blackbird Has Vanished (Updated)
https://historynet.com/unstart-over-murmansk/

> “The airplane yawed to the right so far and so fast, it felt like it was going sideways!” said Osterheld. The SR-71’s right engine had just experienced an “intake unstart.”

Doesnt seem like a "hiccup" would "tear apart" if one engine failing entirely (intake unstart) didn't.

addisonl··on Moderna reports first positive Phase 3 for mRNA neoantigen therapy in melanoma
Misleading comment.

From https://onlinelibrary.wiley.com/doi/10.1002/ijc.35463

> Cutaneous melanoma (CM) accounted for around 331,700 cancer cases globally in 2022

> An estimated 267,353 (95% uncertainty intervals [UI]: 242,818, 278,638) CM cases were UVR attributable globally in 2022

UVR = Ultraviolet radiation

Cutaneous melanoma (CM) is the vast majority of melanoma cases in the US at least:

> The percentages of melanomas that were cutaneous, ocular, mucosal, and unknown primaries were 91.2%, 5.2%, 1.3%, and 2.2%, from https://pubmed.ncbi.nlm.nih.gov/9781962/

tl;dr ~80% of Cutaneous melanoma cases are attributable to UV exposure.

addisonl··on Moderna reports first positive Phase 3 for mRNA neoantigen therapy in melanoma
> This also means that you are likely to get melenoma form something other than the sun.

Quantifiably false statement. Incredibly dangerous misinformation to spread—shame on you.

From https://onlinelibrary.wiley.com/doi/10.1002/ijc.35463

> Cutaneous melanoma (CM) accounted for around 331,700 cancer cases globally in 2022

> An estimated 267,353 (95% uncertainty intervals [UI]: 242,818, 278,638) CM cases were UVR attributable globally in 2022

UVR = Ultraviolet radiation

Cutaneous melanoma (CM) is the vast majority of melanoma cases in the US at least:

> The percentages of melanomas that were cutaneous, ocular, mucosal, and unknown primaries were 91.2%, 5.2%, 1.3%, and 2.2%, from https://pubmed.ncbi.nlm.nih.gov/9781962/

addisonl··on Show HN: I built a 2-min quiz that shows you how bad you are at estimating
> Question: A fair die rolling a 6 twice in a row is more likely than rolling 1-2-3-4-5-6 in sequence

Two 6s in a row is 1/36 chance (1/6)^2

1-2-3-4-5-6 is a 1/46656 chance (1/6)^6

Website is claiming they are the same probability:

> Same probability: 1/46,656 — Both outcomes have exactly the same probability: (1/6)^6 = 1/46,656. This illustrates the representativeness heuristic — random-looking sequences feel more probable than ordered ones.

Website's "answer" is wrong: was the question supposed to be rolling a 6 six times in a row?

addisonl··on Eat Real Food
Its actually not "pretty clear"—about 25-30% of people are hyper responders who are impacted by dietary cholesterol.
addisonl··on AI-generated art lacks copyright protection, D.C. court says
I mean these analogies could be applied to AI image gen too. Open up an image gen tool and press generate. Do you get a great image? No, because you didn’t even enter a prompt.
addisonl··on DMV tells Cruise to reduce its driverless vehicle fleet in SF by 50%
Cruise has been operating in Phoenix for many years now.
addisonl··on YouTube using antipattern to force people enable history
I love and share this view—whenever a website uses dark patterns like this to try and get me to do something I just close the website and thank them for helping me reduce my screen time!
addisonl··on Musk: Block is going to be deleted as a “feature”, except for DMs
Best way to block people on Twitter after this: delete Twitter.
addisonl··on X apparently added 5-second delay for links to sites Musk doesn’t like
A temporary outage that only impacted sites that happened to critique or compete with Musk?
addisonl··on LK-99 isn’t a superconductor
> HN discussion did not particlarly have "reasonable skepticism".

That’s definitely not true despite your attempts to gaslight us.

addisonl··on Cruise vehicle gets stuck in wet concrete while driving in San Francisco
> If that claim breaks down whenever the driving conditions are anything other than perfect, then self driving cars lose their only supposed benefit

False dilemma: value from self driving cars is a sliding scale, not all or nothing.

addisonl··on Webvan: The dotcom bubble’s biggest bust
> The biggest beneficiary of Webvan’s failure was Amazon.com. Not only did the company learn from the mistakes made by Webvan, but it also hired former Webvan executives to launch its own grocery delivery service: Amazon Fresh. Further, in 2012, Amazon bought KIVA Systems, a company that developed the robotic technology initially used in Webvan distribution facilities, for $775 million. Amazon even owns the domain webvan.com.

Never heard of this company before but found this very interesting. Good read.

addisonl··on Being a short-term rental host has become much harder
Strawman: no one said loud guests are the norm.
addisonl··on Why heart attacks are rising in young adults and what to watch out for
You have any studies stating the opposite, that heart attacks are falling for folks under 50?
addisonl··on Tesla committed fraud by “grossly” exaggerating EV range, class action says
On top of that, my car can remember the MPGs I got for the last tank (and every tank before that) and estimates my range off of that. Apparently that’s “magic” according to the comment you replied to. Tesla apologists always have some excuse.
addisonl··on Senate votes to let people who’ve used marijuana work at intelligence agencies
Wealthiest religion in the world, they have massive real estate holdings.
addisonl··on LK-99: The live online race for a room-temperature superconductor
This has been asked over and over again in this thread.
addisonl··on Large language models, explained with a minimum of math and jargon
> Please don't pick the most provocative thing in an article or post to complain about in the thread. Find something interesting to respond to instead
addisonl··on Scientists may have found mechanism behind cognitive decline in aging
Well, considering it was trained from content created from how people actually write, yes?
addisonl··on One in five Texans lives in a floodplain, state’s first-ever analysis shows
Hasn’t TX had multiple years of grid failures? Not really a “black swan event” if it keeps happening.
addisonl··on Tesla created secret team to suppress thousands of driving range complaints
“The organization also found that Tesla, which is often lauded for its sophisticated technology, was not a paragon of reliability, ranking dead-last among brands”
addisonl··on Tesla created secret team to suppress thousands of driving range complaints
Tesla is one of the least reliable brands you can buy: https://www.jdpower.com/business/press-releases/2023-us-vehi...

Only Ford/Lincoln, Audi, and Land Rover are worse—all notoriously unreliable brands.

addisonl··on Florida ocean temps surge to 100F; mass coral bleaching event is found in reefs
You’re in this thread multiple times saying “5 million years ago…” “3 million years ago…” no one is fooled by your attempts to gaslight us on how serious our situation is today.
addisonl··on Remote work on HN: Who is hiring? – 69% jobs in 2023 are remote
And people wonder why companies don’t like remote work…
addisonl··on Chinese Cars Are Good Now and We All Need to Get Used to It
Definitely don’t agree with this at all. Go sit in a VW then sit in an Audi, or Toyota/Lexus, Hyundai/Genesis and tell me they are of the same quality. They are not.
addisonl··on Chinese Cars Are Good Now and We All Need to Get Used to It
Oh don’t get me wrong, I test drove the Polestar 2 and liked it—miles better interior than the Model 3—but them being made in China was a deal breaker. I’m trying to buy less things made in China and dropping $60k on a Chinese vehicle doesn’t really fit that goal. Plus the shady software as you mention.
addisonl··on Show HN: LLM Assistant to Navigate Regulations
How do you ensure what the LLM generates is legally accurate?
addisonl··on Chinese Cars Are Good Now and We All Need to Get Used to It
Personally I’d never buy a car made in China. Related, I find it pretty strange Volvo is trying to establish a luxury brand (Polestar) but instead of building Polestars in Sweden they are building them in China.
addisonl··on Shopify employee breaks NDA to reveal firm replacing laid off workers with AI
> probably 90% of people are like this

I think you’re overestimating the average person.

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