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alan-hn

407 karma · joined February 4, 2022

Scientific software engineer, pharmacologist, neuroscientist
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alan-hn··on The unreasonable effectiveness of plasmid sequencing as a service
Some labs do but that is a bunch of extra labor that they need to manage. Sometimes some labs do more sequencing than others and they might have more researchers to do the regular sequencing. Many labs are smaller and can't afford to hire so many people or buy so much tertiary equipment. Grad students are already overloaded so they probably don't sequence unless its directly a part of their project
alan-hn··on In SSRI withdrawal, brain zaps go from overlooked symptom to center stage (2023)
MDMA generally wouldn't cause the brain zaps after normal use (one 120-180mg dose), its usually high doses or abuse over multiple days that causes the changes necessary to feel these symptoms
alan-hn··on How long til we're all on Ozempic?
>The majority of people who are accessing this drug have endocrine systems that work just fine, but problems with controlling themselves around food

Quite frankly this is an incredibly absurd statement. Do you realize that our brains entirely control our behavior? An issue with self control is a brain issue, and very well may be an endocrine issue. Are you an endocrinologist?

alan-hn··on The profit-obsessed monster destroying American emergency rooms
So why does a PhD university professor make less than a wall st trader frat bro
alan-hn··on The profit-obsessed monster destroying American emergency rooms
Money and greed naturally get in the way. Is that not obvious? People are finding any way to game the system just to get more money

You're thinking of using money as a measure but everyone else is using it as a target...

alan-hn··on The profit-obsessed monster destroying American emergency rooms
This is because its the profit focus of capitalism that is exactly the problem

Its a disconnect powered by propaganda of the definition of "success"

alan-hn··on OpenAI to Become For-Profit Company
I think the people getting salaries are doing just fine
alan-hn··on 1970 Clean Air Act was intended to cover carbon dioxide
Then you get loopholes being abused
alan-hn··on FBI Complains About Encryption Making It Difficult to Scrape Dead Person's Phone
From what I'm aware they can get the key by physically milling a chip on the board to get access to memory, but they take evey opportunity to complain so that companies might be forced to install backdoors
alan-hn··on Indian police pinpoint seat of movie camming pirate by analyzing the film angle
Both of these comments show the incredibly sad state of affairs when it comes to law enforcement worldwide
alan-hn··on It's not just us: Other animals change their social habits in old age
Cortisol can actually act as a painkiller and reduces inflammation allowing us to work through injury
alan-hn··on Creativity fundamentally comes from memorization?
Exactly, everyone here is just describing different forms of memorization
alan-hn··on [dead]
But will the agents care or listen?

My instincts say probably not

alan-hn··on Maglev titanium heart inside the chest of a live patient
Here is one from Carmat that is already in use in Europe

https://www.carmatsa.com/en/our_product/

alan-hn··on [dead]
https://archive.is/j88xv
alan-hn··on Every company should be owned by its employees
Why on earth would you pay each person 16 million per year? That's 1%

You can still make everyone's wages better without paying millions to each person and definitely not to the CEO

alan-hn··on China doubles subsidies for EVs in its 'cash for clunkers' program
The teslas that also have a ton of QC issues? I'd rather trust a long time car manufacturer like Honda, BMW, Audi, or Nissan when it comes to EVs
alan-hn··on Show HN: AI over Email
I did all the same things and even registered my domain with google and added their verification DNS txt record. You're probably right about it being linode's IP range, although I did get permission from linode to use it as a mail server, they opened the right ports and I did get deliverability to other mail hosts just not google or my university at the time, annoyingly enough
alan-hn··on MPPP – The first 'designer drug' disaster (2023)
You're using a lot of hyperbole. Nobody said anything about building societies on drug addicts. Overdoses primarily happen due to users not knowing how strong their mixture is, they also happen frequently in new settings and after a period of abstinence. These are all things that have been shown in the literature.

I love how you also ignored the rest of my points about whose society you're referencing.

Do you work in the drug or addiction field?

alan-hn··on MPPP – The first 'designer drug' disaster (2023)
Whose society? Western society? What about Mexican society? South america? The native Americans used psychedelic cactus and mushrooms. You seem to be drawing relatively arbitrary lines based on your own biased upbringing

And we don't have to choose only one, that's arbitrary too. We can easily dismantle the current prohibitory system to allow for a system of regulated production and access which would improve safety and reduce overdose deaths. Most overdoses happen because of the nature of the black market. There is no regulation or testing so substances, particularly opioids, can get cut to unknown potencies depending on the person handling it. This makes it a gamble every time a person were to use rather than consuming a measured amount of a pure substance. Prohibition objectively increases harm to individuals, society, and the economy.

alan-hn··on Show HN: AI over Email
I had a personal email server on linode for a while but a lot of my family uses gmail. Gmail wouldnt accept my emails and I ended up switching my domain to a commercial provider because it was such a pain in the ass. Never did mass emails or marketing, just my own personal use
alan-hn··on MPPP – The first 'designer drug' disaster (2023)
Are you arguing that adults should not be able to choose what they ingest because some people used to give opium to babies at one point?
alan-hn··on Show HN: AI over Email
Does it sit behind a clean IP? Had any problems sending to gmail or other big providers?
alan-hn··on MPPP – The first 'designer drug' disaster (2023)
The US forced their system of controlling psychoactive substances on the rest of the world through treaties primarily. Perhaps you should learn about the history of drug use and control.

You also didn't answer my question about alcohol. Why is it legal and not cannabis?

alan-hn··on MPPP – The first 'designer drug' disaster (2023)
Using psychoactive drugs is incredibly normal and has been practiced for thousands of years by humans. In fact it is one of the most human things you can do because many other species don't exhibit this behavior. We should be working in the interest of reducing stigma of drug use to reduce harms associated with it. Drugs are illegal because politicians wanted a way to crack down on communities that didn't agree with their policies, it is simply a form of control. Have you never asked why alcohol is legal and cannabis or LSD are illegal? Fear and control.
alan-hn··on MPPP – The first 'designer drug' disaster (2023)
Neurons usually handle that automatically. They are able to detect chemical signal and send out projections being axons or dendrites on their own
alan-hn··on Why I Buy German Toothpaste Now: Hydroxyapatite to Fight Cavities Works
I've been using hydroxyapatite toothpaste for a while now. Tried a few brands but landed on David's toothpaste and I like it quite a bit. Less sensitivity in general and my dentist says my teeth have been great

https://davids-usa.com/products/davids-sensitive-whitening-n...

alan-hn··on Sharks test positive for cocaine in waters off Brazilian coast
D2 is a specific subtype of dopamine receptor not a dopamine transporter. The dopamine transporter is DAT which is inhibited by cocaine along with NET and SERT
alan-hn··on Bangladesh imposes curfew after dozens killed in anti-government protests
You're right, that's too gentle of phrasing. Fascism is a 100% far right ideology. Please excuse my Ameribrain, I'm continuously bathed in conservative capitalist and neoliberal propaganda
alan-hn··on Study reveals how anesthesia drug propofol induces unconsciousness
And there's the unconvincing nonsense I mentioned in my other comment

Its like a bunch of science buzzwords strung together

Quantum AI blockchain!

I think its completely absurd and throws out what we actually know about computations that do happen in the brain

"Orch OR has been criticized both by physicists[14][53][37][54][55] and neuroscientists[56][57][58] who consider it to be a poor model of brain physiology. Orch OR has also been criticized for lacking explanatory power; the philosopher Patricia Churchland wrote, "Pixie dust in the synapses is about as explanatorily powerful as quantum coherence in the microtubules."[59]"

https://en.m.wikipedia.org/wiki/Orchestrated_objective_reduc...

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