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4,414 karma · joined December 12, 2007

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car··on You Can Just Buy Far-UVC
I've built 12V mercury vapor UV-C (254nm) lights for fluorescent mineral hunting, and that wavelength is quite harmful, requiring skin and eye protection. Mercury vapor lamps produce a spectrum of wavelengths, also in the visible spectrum, which gets filtered out since it distracts.

According to this [1] article, the 222nm range is safe for exposure, but the Krypton-Chloride bulb in the far-UVC lamp does also produce harmful wavelengths (256nm), therefore a filter is absolutely necessary. Thankfully simple plastics should work fine for that.

I would still be extremely careful deploying these lights in occupied spaces.

Edit: Come to think of it, filtering the harmful UVC (256nm) from KrCl excimer lamps with acrylic would probably also block the far-UVC. Which makes me wonder what material the filter is. Regular glass stops UVC, which is why UVC lamps are usually quartz or special glass formulations.

"What really needs to be understood is that an unfiltered 222nm Far-UV peak from any KrCl excimer lamp emits a wide band of wavelengths starting at 200nm, past the human safe zone of less than 230nm, all the way to the end of the UVC spectrum at 280nm -- with a very worrisome second harmonic peak at 256nm."

"the 222nm excimer lamp's second harmonic peak at 256nm exclusive to KrCl Far-UVC lights should be treated no different than the well-established carcinogenic hazards involved when using 254nm mercury-line UVC germicidal bulbs."

[1] https://www.prweb.com/releases/222-nm-far-uvc-cancer-risk-wi...

car··on Accepting US car standards would risk European lives
Did I hear that right, dream car vs. asshole bucket?
car··on How to make precise sheet metal parts (photochemical machining) [video]
Along these lines, a current Kickstarter project, which uses a 3D printer and a saltwater jet in a very clever way to ablate metal electrochemically. It even presents the prospect of doing metal deposition printing by reversing the process/current (skip to 9:50).

https://www.kickstarter.com/projects/athenatech/liquid-blade...

car··on Deep Learning Without Training
Goldilock's "miracle" - a result enabled by the Riemann zeta function's log prime basis (Euler prime product)

podcast: https://www.youtube.com/watch?v=RH9-CQxdDJw

car··on NeXT Computer Offices
„Ankle Deep Shit“
car··on Less Is More: Recursive Reasoning with Tiny Networks
Interesting review of the paper:

https://www.linkedin.com/posts/a-roucher_stop-everything-now...

car··on How to make almost anything (2019)
There is also the amazing MIT synthetic biology class 'How to Grow (Almost) Anything' by David Kong and George Church. I took it during the pandemic, and it was great. It's open to anyone, but requires quite a bit of commitment.

https://howtogrowalmostanything.notion.site/htgaa25

car··on The Gottorf Globe and its reconstruction
Putin once visited here.
car··on The Roman Roads Research Association
Prehistoric fields have also been identified with Lidar.

https://celtic-fields.com

car··on Show HN: Zenta – Mindfulness for Terminal Users
Thank you for being so responsive, and making Zenta in the first place! It has already allowed me to calm my mind on a few occasions.

The cli is already so bare bones and focused, so Zenta fits in well.

car··on Show HN: Zenta – Mindfulness for Terminal Users
Great.

I only get a line animation in the MacOS terminal app, under zsh, it doesn't look like the description.

car··on Snow - Classic Macintosh emulator
Feels so real, great work.

Any chance this could be made to emulate an Atari ST?

car··on Functional MRI can do more than you think
As an almost radiologist, it’s exciting to see how MRI technology is making these strides.

Another area that seems to be coming into its own is using hyperpolarized isotope Carbon 13 as a contrast agent. It can be incorporated into metabolites like pyruvate and show tissue with rapid uptake. This is used in the detection of cancer, where the cells are extremely hungry for glucose/pyruvate, a phenomenon known as the Warburg effect.

https://hyperpolarizedmri.ucsf.edu/

https://en.m.wikipedia.org/wiki/Warburg_effect_(oncology)

car··on Study: Even richest Americans face shorter lifespans than European counterparts
And even worse:

The researchers also highlighted a “survivor effect” in the U.S., where poorer individuals with worse health outcomes were more likely to die earlier, leaving behind a population that is healthier and wealthier as age groups progress. This creates the illusion that wealth inequality decreases over time, when in reality it’s partly due to the early deaths of the poorest Americans.

“Our previous work has shown that while wealth inequality narrows after 65 across the U.S. and Europe, in the U.S. it narrows because the poorest Americans die sooner and in greater proportion,” Papanicolas said.

car··on Ask HN: can Wireless-CarPlay dongles steal your data?
CarPlay sends a H264/5 video stream from the iPhone to the car's head unit, and receives touchscreen, knob, etc. input in the other direction (afaik). I'm not sure if the video is encrypted, but it seem rather unlikely that the dongle could exfiltrate such an amount of data undetected.
car··on Show HN: Open-Source DocumentAI with Ollama
That would be great. Llama.cpp’s built in server offers HTTP embedding endpoints.
car··on Show HN: Open-Source DocumentAI with Ollama
Could this work with llama.cpp, since it’s the engine behind Ollama?

I usually build llama.cpp from source and download quantized (GGUF) models from Huggingface, haven’t used Ollama this far.

car··on Ketamine for Depression: How It Works (2024) [video]
In all this discussion, I’d like to add a piece of interesting recent scientific discovery regarding the mechanism of action that might well explain the increase in neuroplasticity from psychedelics like psylocibin and LSD and offers hope that we will find drugs that have the positive neuroplasticy increasing effect without causing hallucinations [1].

Below the abstract of the mentioned research (BDNF is Brain Derived Neurotrophic Factor, a kind of growth hormone for the brain), note the 1000 fold(!) higher affinity of the psychedelics:

Psychedelics produce fast and persistent antidepressant effects and induce neuroplasticity resembling the effects of clinically approved antidepressants. We recently reported that pharmacologically diverse antidepressants, including fluoxetine [= SSRI] and ketamine, act by binding to TrkB, the receptor for BDNF. Here we show that lysergic acid diethylamide (LSD) and psilocin directly bind to TrkB with affinities 1,000-fold higher than those for other antidepressants, and that psychedelics and antidepressants bind to distinct but partially overlapping sites within the transmembrane domain of TrkB dimers. The effects of psychedelics on neurotrophic signaling, plasticity and antidepressant-like behavior in mice depend on TrkB binding and promotion of endogenous BDNF signaling but are independent of serotonin 2A receptor (5-HT2A) activation, whereas LSD-induced head twitching is dependent on 5-HT2A and independent of TrkB binding. Our data confirm TrkB as a common primary target for antidepressants and suggest that high-affinity TrkB positive allosteric modulators lacking 5-HT2A activity may retain the antidepressant potential of psychedelics without hallucinogenic effects.

[1] https://www.nature.com/articles/s41593-023-01316-5

car··on [dead]
https://tiefling.app
car··on Mercury's shadowy North Pole revealed by M-CAM 1
Wondering same. If my math is right, this was a 1/25 sec. exposure. (40/1000)
car··on IRATA.ONLINE: A Community for Retro-Computing Enthusiasts
For context:

Donald Bitzer, a pioneer of cyberspace and plasma screens, dies at 90

He helped shape cyberculture as the father of PLATO, a computer-based educational network that sparked the development of plasma screens and digital messaging.

https://www.washingtonpost.com/obituaries/2024/12/13/donald-...

https://news.ycombinator.com/item?id=42406158

car··on IRATA.ONLINE: A Community for Retro-Computing Enthusiasts
https://www.youtube.com/watch?v=tTmWcGhlXqA
car··on A New Phone Scanner That Detects Spyware Has Found 7 Pegasus Infections
Pertinent and timely, after recently watching a great documentary on HBO Max about Pegasus, Surveilled by Ronan Farrow.

Commercial spyware, touted as a tool used by governments to fight terrorism, is now appearing on the phones of activists, journalists, politicians, and even ordinary people. In Surveilled, Pulitzer Prize-winning journalist Ronan Farrow illuminates a clandestine industry that is reshaping the concepts of privacy and power, revealing the ethical dilemmas that both governments and citizens must navigate in the brave new world of cyberespionage.

HBO Documentary Films presents Surveilled. Producers and directors, Matthew O’Neill and Perri Peltz; producers, Ronan Farrow, Beth Morrissey, and Unjin Lee; editor, David Meneses; composer, Mac Quayle; writers, Ronan Farrow, Matthew O’Neill, and Perri Peltz. For HBO: executive producers, Nancy Abraham, Lisa Heller, and Sara Rodriguez.

[1] https://www.hbo.com/movies/surveilled

car··on EstyJS 2.0 (emulator for the Atari ST, written in 100% pure JavaScript)
You actually can do that by pressing the 'lock' button below the 'monitor'.
car··on EstyJS 2.0 (emulator for the Atari ST, written in 100% pure JavaScript)
What's with the influx of Atari ST postings lately? I'm surely enjoying it!

Can EstyJS run in monochrome (640 x 400) mode? There were some great games in b&w, like Bolo and Oxyd [0] by Meinolf Amekudzi.

I remember studying the 'Hitchhikers Guide to the BIOS' [1], which was the only piece of documentation I initially had for the ST when it had just come out. If I'm not mistaken, it did ship with a C compiler and assembler.

[0] https://www.atariuptodate.de/en/authors/meinolf-amekudzi-104...

[1] https://archive.org/details/rearc_atari-st-e-tt-toolkit-b1-3...

car··on MIT Aluminum Bicycle Project 1974
A modern alternative are bamboo frames, e.g. https://my-boo.de
car··on Starlink Direct to Cell
I heard that Google's project Loon was having issues with LTE time outs due to the distance of the balloons LTE antenna from the ground. How does this square with the much larger distance of LEO satellites?
car··on The deep learning boom caught almost everyone by surprise
It’s all in the architecture. Also, biological neurons are orders of magnitude more complex than NN’s. There’s a plethora of neurotransmitters and all kinds of cellular machinery for dealing with signals (inhibitory, excitatory etc.).
car··on GLP-1s are among the most important drug breakthroughs
Can you elaborate on the alternative source?
car··on GLP-1s like Ozempic are among the most important drug breakthroughs ever
https://archive.is/aVVg0
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