750 karma · joined October 10, 2020
Tons of drugs in the pipeline that goes after these promising receptor targets. PD-1/PD-L1, CD47, CD40 (as mentioned in the article) etc. Keytruda (PD-1) is an incredible success both clinically and commercially, but there are many many other drugs buried in the clinical trial cemetery that initially showed promising results.
Medicine is really hard.
All machine learning is AI, not all AI is machine learning.
The level of talent Apple has cannot be understated, they have some true CPU design wizards. This level of efficiency cannot be achieved without making every aspect of the CPU as fast as possible; their implementation of the ARM ISA is incredible. Lots of companies make ARM chips, but none of them are Apple level performance.
As a gross simplification, where the energy/performance tradeoff actually happens is after the design is basically baked. You crank up the voltage and clock speed to get more perf at the cost of efficiency.
I would much rather have a A6 or A5 sized display or any other standard size for paper notebooks.
All the more reason to believe that while correlated, LLMs are certainly not the largest contributor, or even the cause of the job market weakness for young people. The more likely and simple explanation is that there are cracks forming in the economy not just in the US but globally; youth employment is struggling virtually everywhere. Can only speculate on the reasons, but delayed effects from questionable monetary and fiscal policy choices, increasing wealth gaps, tariffs, geopolitics, etc. have certainly not helped.
There are so many cultural factors in SK that might take generations to reverse without being "forced" by the government (which is also wary to enforce). Of course, by then its too late per the video.