felixbraun

Agree, if seen as start/inception of a line: promising

Imagine them boiling this down over the years into a ‘battle tested’ streamlined 160k EV -- they do not require the first version to be sold much ‘at all’ at this price point; it is now out there and the goal seems to be to mark the top of the line of this segment longterm; and if this succeeds, they ported the co into the future in style

There is soo much great design in this but it might be required to get closer to really experience and appreciate

So likely longterm: very good move

5h and weekly resets remain, but the quotas are now ‘filled’ differently?

Already live in Cursor btw

Excellent work — reminds me of similar projects built with the same tech stack:

– Coins: A journey through the Münzkabinett Berlin collection (one of the largest in the world). https://uclab.fh-potsdam.de/coins/

– Theodor Fontane Marginalia: A visualization of Fontane’s marginalia and notes in his personal library. https://uclab.fh-potsdam.de/ff/

Just leaving this here — you are up to something. Karpathy:

> Products with extensive/rich UIs lots of sliders, switches, menus, with no scripting support, and built on opaque, custom, binary formats are ngmi in the era of heavy human+AI collaboration.

If an LLM can't read the underlying representations and manipulate them and all of the related settings via scripting, then it also can't co-pilot your product with existing professionals and it doesn't allow vibe coding for the 100X more aspiring prosumers.

Example high risk (binary objects/artifacts, no text DSL): every Adobe product, DAWs, CAD/3D Example medium-high risk (already partially text scriptable): Blender, Unity Example medium-low risk (mostly but not entirely text already, some automation/plugins ecosystem): Excel Example low risk (already just all text, lucky!): IDEs like VS Code, Figma, Jupyter, Obsidian, ...

AIs will get better and better at human UIUX (Operator and friends), but I suspect the products that attempt to exclusively wait for this future without trying to meet the technology halfway where it is today are not going to have a good time.

https://x.com/karpathy/status/1930354382106964079?s=61

related discussion (3 days ago): https://news.ycombinator.com/item?id=40508390

It needs to be settled if listening to a voice (as an AI) and approaching to recreate/imitate it with your own system/tech is legal (which I believe) -- this 'her' confrontation seems to be the perfect angle to feel into the legislature here without much to lose

> for this thread, let's make a key rule: do not use your browsing tool (internet) to get info that is not included in your corpus. we only want to use info in corpus up until dec 2023. if you feel you need to use browsing to answer a question, instead just state that the required info is beyond your scope. the only exception would be an explicit request to use the browsing tool -- ok?

Worked on an open source cloud player 10y ago: idea was to have one place to curate playlists and your music library in general -- basically an access and authentication platform where the underlying providers can change over the years without impacting your collection.

Still feel this is the right way to think about collecting and curating music going forward…

Recent article with more details about the current state of Soundcloud – ("achieved eight consecutive months of profitability"):

https://www.musicbusinessworldwide.com/spotify-chasing-annua...

I doubt that it's possible to target "healthy bacteria" with diet prebiotic plant fiber (probiotics are bacteria and won't "feed", you're right) -- it's random, unfortunately.

Low endotoxin load > health effects of butyrate etc, if you have serious issues like IBS or crohns

Doing the exact opposite might help — probiotics feed harmful bacteria as well and a different strategy would be to simply try to keep your microbiome as basic and unintrusive as possible, allowing the gut to calm and heal.

It’s easier said than done; recommend looking into natural antibiotics (eg cooked white button mushrooms), indigestible fibre to ensure regular movements, which more than anything lowers endotoxin load (raw carrot salad), carbs from sugars instead of starch, which get absorbed more quickly and won’t be very “prebiotic” (eg ripe oranges, honey) and nutrient dense foods to meet metrics (organ meats and cheeses).

And then Luna happened, sealing their fate

Oxysterols seem to stimulate amyloid beta formation in the liver and even in the brain directly:

> We have shown that patients with AD have increased brain levels of 27-hydroxycholesterol, which may affect the production of beta-amyloid.

https://pubmed.ncbi.nlm.nih.gov/16866910/

avoid oxidized lipids and especially oxysterols

very good primer: https://csroldsite.wordpress.com/2013/03/04/oxysterols-the-t...

Interesting to see Mastercard, Square, Stripe, FIS, Fiserv and Visa all mentioned in "Market Participants".

None of those actively today use/settle stablecoins publicly?

So looking forward to the next version of iPhone 4 — hopes higher than ever

I’m very sure that there is more money (for big high volume exchanges) in providing an environment with low liquidations (which amplify price moves against the index, again bad UX) instead of driving customers into them and profiting from trading these wicks.

The biggest risk to established exchanges is ‘regulatory alienation’ — and having millions of USD in daily liquidations probably is not helpful here.

Won’t say these trades aren’t done (data needed to build positioning models is public), my only point here; v unlikely by exchange owners.

IMO people overestimate how much alpha is in knowing your customers’ positions (as exchange owner).

Open interest, volume and price data down to seconds is available via APIs in real-time, from which it is absolutely possible to build a model of positioning.

If you launch a new exchange, your biggest problem is lack of liquidity, meaning limit orders won’t fill ‘timely’ and market orders slip, which is very bad UX obviously.

That is why it is fairly obvious that one of the best market makers in the industry launched their own exchange; Alameda could provide excellent liquidity for FTX from day one.

> Consumers spent $6bn on Onyfans last year. If the payment industry won't or can't support that, this is another arbitrage opportunity, like it or not. Is there a payment tech that doesn't have centralised gatekeepers, and uses a bearer model to address fraud?

https://twitter.com/benedictevans/status/1428737349979095040...

They have $1.7b in the insurance fund and take in $300-500m / yr (easy calculation if you know their fees and volume, which is known to be "real"; Bitmex is absolutely legit and it is disturbing that charges against their founders continue)

You could check for T-cells at some point -- if you had Covid, they are measurable even after many months. In contrast, IgG titers show up in only ~80% and decline steadily. Excellent recent paper:

> Here, we investigated SARS-CoV-2 antibody and T cell responses in matched samples of COVID-19 convalescent individuals up to 6 months after infection. Longitudinal analysis revealed decreasing and stable spike- and nucleocapsid-specific antibody responses, respectively. In contrast, functional T cell responses remained robust, and even increased, in both frequency and intensity.

https://stm.sciencemag.org/content/13/590/eabf7517

It seems to be very unlikely that brain cysts (that might affect cognition) can form in immunocompetent people — a pathological study of AIDS patients showed cysts in ~20%; background seropositivity in France (where the study was conducted) is ~40%.

Conclusion by the authors: the amount of toxoplasmic agents appeared to be related to the degree of deterioration of the immune status.

> Neuropathological studies in the brains of AIDS patients with opportunistic diseases: https://pubmed.ncbi.nlm.nih.gov/8518200/

So as the dusk settles -- this whole BTC and DOGE drama was intended as an indirect lesson to not short TSLA and keep their stock in range where it is completely removed from fundamentals for just a little bit longer?

Readmill (acquired by Dropbox) was a better Goodreads -- there is no app I miss more

https://www.youtube.com/watch?v=5DTNCLSoMho

"VW secures US$25B in battery supplies in electric-car surge" https://www.bnnbloomberg.ca/vw-secures-25-billion-battery-su...

"Volkswagen will invest almost 1 billion euros ($1.1 billion) in battery cell production at a facility in western Germany" https://www.reuters.com/article/us-volkswagen-electric/volks...

Carnivore diversity was much higher in the Late Pliocene -- which means more frequent and varied scavenging opportunities.

There might have been a very small, precious window where early hominins had the chance for this discovery because of abundance.

[1] Origins of the Human Predatory Pattern: The Transition to Large-Animal Exploitation by Early Hominins: https://www.journals.uchicago.edu/doi/abs/10.1086/701477?jou...

Since non-diabetics accumulate close to zero Titanium Dioxide and it is ubiquitous in our 'modern' environment, it seems more likely that diabetics have for some reason difficulties clearing these crystals?

+1, might add this TED Talk by the author of "Gut"

https://www.youtube.com/watch?v=HNMQ_w7hXTA

Yogurt Containing Lactobacillus gasseri Mitigates Aspirin-Induced Small Bowel Injuries: A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial.

https://www.ncbi.nlm.nih.gov/pubmed/28052291