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ironchief

1,500 karma · joined February 3, 2011

3D Organ Printing (United Therapeutics $UTHR)

Death is a disease. Cure it.

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ironchief··on My Friend Bob Cringely
His Steve Jobs “Lost Interview” is also the best Steve Jobs interview. Highly recommend taking the time to watch it. https://youtu.be/Bbwj58Xj2yI?is=J5w7WWg3-AegCwbf
ironchief··on My Friend Bob Cringely
He messaged me a couple years ago and it matches with this post's description: "While the first half of the email was about the idea, invariably, the 2nd half was about how much money it was going to make."

  Point-to-point supersonic organ delivery

  Dear Derek,

  I'm Bob Cringely, an ancient Silicon Valley pundit. I also run a little
  CubeSat air-launch startup. Competition from SpaceX forced us to cut costs
  so we figured how to make an old French business jet fly Mach 1.6 on the
  fuel to fly Mach 0.8. Now we want to apply this tech to organ delivery.
  100 VTOL supersonic drones could serve the whole US operating from helipad
  to helipad at 1000 mph. Not autonomous, they'll have pilots on the ground.
  It's a $2 billion business with 75 percent margins but only we know how.
  Please pass it on.
ironchief··on South Pole Water Infrastructure
More info on the PM-3A reactor http://large.stanford.edu/courses/2014/ph241/reid2/
ironchief··on Was Apple’s 1999 Power Mac G4 Classified as a Weapon? (2014)
Fascinating that High Performance Computers had export controls in the 90s as dual use technology but little restraint until recently.

How would we apply this today? Instead of MTOPS use TFLOPS FP16?

ironchief··on Head of election worker management company arrested for theft of personal data
I thought your comment was a joke until I read the link. Wow

"District Attorney investigators found that in contradiction to the contract, information was stored on servers in the People’s Republic of China."

ironchief··on Viewpoints Research Institute concluded its operations at the beginning of 2018
Every org that hired Alan Kay as a fellow was closed

- Apple Advanced Technology Group

- Walt Disney Imagineering Fellows

- HP Advanced Software Research

- VPRI

ironchief··on Raiders of the Lost Ark as a Black-and-White Silent Film (2014)
Do you have the link to the documentary?
ironchief··on Filecoin: Proof of Storage Systems
This hardly meets the definition of brief description, let alone a "Deep Dive".
ironchief··on Y Combinator has lost its soul: A YC founder's perspective
I recommend reading this blog post and drawing your own conclusion.

My conclusion is PG's "I can lay out what I know to be the right thing to do, and still not do it."

ironchief··on Chan Zuckerberg Initiative scientists: FB’s practices ‘antithetical’ to mission
Yes.
ironchief··on India is easing sourcing norms for single-brand retailers like Apple
“To boost sales in India, Apple has started to assemble several iPhone models locally and reached a stage where it can begin to export to overseas markets phones produced in India. Assembling phones in India allows Apple — as it does to other phone makers — to enjoy some tax benefits that Narendra Modi’s government provides.“
ironchief··on India is easing sourcing norms for single-brand retailers like Apple
Apple - We can't make iPhones in the US and tariffs don't work

Also Apple - Tariffs made us move production to Brazil and India.

ironchief··on [dead]
"Men are chronically lonely and unable to express their pain. Women hardest hit." - @olivertraldi
ironchief··on Why is there no US rival to compete with Huawei?
"I wonder if the so-called developed countries should be careful of their own premature deindustrialization. The US industrial base has faltered, but there is still so much left to build. Until we’ve perfected asteroid mining and super-skyscrapers and fusion rockets and Jupiter colonies and matter compilers, we can’t be satisfied with innovation confined mostly to the digital world."

I highly recommend reading Dan Wang's "Definite optimism as human capital" https://danwang.co/definite-optimism-as-human-capital/

ironchief··on Israeli Scientists 'Print' World's First 3D Heart with Human Tissue
It is not. This is another example of "looks like, but doesn't work like". You often see people print noses, ears, whatever that have cells in them. That doesn't make it functional tissue.

Source: I lead a tissue engineering project to print human organs for transplantation.

ironchief··on Mapping San Francisco's Human Waste Challenge
Former Democrat Gov. Jerry Brown vetoed the safe injection site bill saying "enabling illegal and destructive drug use will never work."

Doesn't look like "the Republican Party at the national level" to me.

https://www.washingtonpost.com/news/powerpost/paloma/the-hea...

ironchief··on Israeli scientists print world's first 3D heart with human tissue
Misleading. This is another example of "looks like, but doesn't work like". You often see people print noses, ears, whatever that have cells in them. That doesn't make it functional tissue.

Source: I lead a tissue engineering project to print human organs for transplantation.

ironchief··on Standardizing WASI: A system interface to run WebAssembly outside the web
These Mozilla blogs are some of the best edited, articulated and illustrated explanations I've seen on the web. I wish more people could put in the resources to help communicate their mission like this.
ironchief··on Marcel Duchamp Interview on Art and Dada (1956) [video]
It is the same reason why Taleb does not accept prizes and Peterson reminds us that "you are not the wave" https://www.youtube.com/watch?v=cmjAVZjLQr8
ironchief··on Updates from YC
Altman (YC) leans into SF

Thiel leans away

Will be interesting to see the winning move

ironchief··on Anxieties of development: emerging voices in Chinese social media
Malthus is wrong and "more people" = "lack of environmentalism" is zero-sum thinking.

Instead consider the positive-sum "We need more people to solve bigger problems" that follows from Esther Boserup's theory. https://en.wikipedia.org/wiki/Ester_Boserup#Work

ironchief··on Reflecting on My Failure to Build a Billion-Dollar Company
Wow, he called the HelloSign acquisition in 2015. His other two suggestions (native search and messaging) are still in limbo.
ironchief··on Golden Thoughts for a New Nuclear Age – from a new biography of René Girard
Girard Startup lessons:

- the founders set a contagious mission that infects the company

- competition can be destructive, work hard to be a monopoly

- the founders take all responsibility and share all success

TLDR; emulate Christ

ironchief··on Tensegrity (1961)
Does anyone have a printable version of this with the figures?
ironchief··on 3 huge new studies of 0.5MM people are casting major doubts on the keto diet
Follow the science, forget the epidemiology/poorly controlled science news.

Sustainability of improved health outcomes (https://link.springer.com/article/10.1007%2Fs13300-018-0373-...)

Rapid impact on type 2 diabetes (https://diabetes.jmir.org/2017/1/e5/)

Significant impact on cardiovascular risk factors (https://cardiab.biomedcentral.com/articles/10.1186/s12933-01...)

ironchief··on SF’s appalling street life repels residents – now it’s driven away a convention
It is and its worse than you think. Here's a 2016 article https://www.sfchronicle.com/bayarea/article/S-F-spends-recor...
ironchief··on Anti-Fascist MIT license
Confirmed. 46% of US voters are fascist.

  "Fascist" can be understood as any entity which supports radical authoritarian
  nationalism. Example: Donald Trump is a fascist, if you donated to his
  campaign then all rights provided by this license are not granted to you.
ironchief··on The Rise and Fall of Thinking Machines (1995)
Great writing by Gary A. Taubes who is now better known for writing about carbohydrates and sugar through books like "Good Calories, Bad Calories"
ironchief··on IBM is not doing "cognitive computing" with Watson (2016)
I'm interested in the original idea. Can you expand on how your ideal system would function?
ironchief··on Tesla's Model 3 volume production target pushed back again
@Tweetermeyer

TESLA TOTAL PRODUCTION BY QUARTER

Q32016: 25,185

Q42016: 24,882

Q12017: 25,418

Q22017: 25,708

Q32017: 25,336

Q42017: 24,565

Anyone else noticing a pattern here?

https://twitter.com/Tweetermeyer/status/948682235892264960

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