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jayzee

2,176 karma · joined December 5, 2010

Jayant, founder: quartzy.com, email: first name at quartzy . com
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jayzee··on PageLever (YC S11) acquired by Unified Social
Congrats Jeff and David!!
jayzee··on Meet YC partners and alums at MIT Wednesday 5:30PM
staff find portfolio
jayzee··on E-commerce startups
The only way to compete is to sell used stuff or make your own products (or provide a marketplace for those things).

Well, there are other markets that fall outside this... For example, at Quartzy we are working in the life-sciences market. There are multi-billion dollar incumbents like Thermo Fisher, VWR, EMD, Sigma and scores of others but the game is different because you are distributing stuff that could be hazardous/require ice/could be radioactive etc. Amazon's warehouses are not equipped (as far as I know) to handle such products.

So one can target markets that have seen no innovation in the last 15 years where Amazon does not have an advantage...

Amazon is getting into lab supplies (glassware etc) but a problem here is that Amazon likes to have one-price and all the manufacturers play a game where there is a list price and a special price at your institution. This is a game for some reason that Amazon does not want to play so in general for a couple of reasons they are locked out for a large fraction of the huge life-sciences market.

Wonder if there are other markets like this out there?

jayzee··on Andreessen-backed virtual workforce MobileWorks (YCS11) does 1M tasks in year 1
This is awesome stuff. I am glad that they are attacking the accuracy angle since for a lot of tasks I care a lot about accuracy and not so much on saving the last $.
jayzee··on Science Exchange Reproducibility Initiative
The part I like about the execution is where you have CROs and Core Facilities, and not scientists themselves validate results. Apparently Milikan when he measured the electric charge was off (smaller than actual) in the measurements... but researchers who checked, worried perhaps about their academic reputation (speculating here) slowly adjusted this number upwards over several years till it asymptotically approached the truth. Having a 3rd-party, that is less impacted by academic politics might be a good thing.

From Feynman's Caltech commencement speech on this:

We have learned a lot from experience about how to handle some of the ways we fool ourselves. One example: Millikan measured the charge on an electron by an experiment with falling oil drops, and got an answer which we now know not to be quite right. It's a little bit off, because he had the incorrect value for the viscosity of air. It's interesting to look at the history of measurements of the charge of the electron, after Millikan. If you plot them as a function of time, you find that one is a little bigger than Millikan's, and the next one's a little bit bigger than that, and the next one's a little bit bigger than that, until finally they settle down to a number which is higher.

Why didn't they discover that the new number was higher right away? It's a thing that scientists are ashamed of--this history--because it's apparent that people did things like this: When they got a number that was too high above Millikan's, they thought something must be wrong--and they would look for and find a reason why something might be wrong. When they got a number closer to Millikan's value they didn't look so hard. And so they eliminated the numbers that were too far off, and did other things like that. We've learned those tricks nowadays, and now we don't have that kind of a disease.

[1] http://www.lhup.edu/~dsimanek/cargocul.htm

jayzee··on Robotic Airplane Flies In Tight Spaces
The difference is not really about the number of variables but the dynamics of the plant...

The classical formulation of Kalman filters assumes gaussian distributions for the variables. This makes the computations much faster since the posterior distributions is a few matrix operations away. This works fine when the model for the plant is linear (since a linear transformation of a gaussian variable is gaussian). In situations where the plant model is not linear estimates can go awry quickly.

In the case of particle filters you sample the prior distribution, simulate the non-linear plant with these initial conditions and then construct the posterior distribution by incorporating the measurements. This process is computationally more expensive than classical Kalman filtering but is more accurate for non-linear plants.

jayzee··on Ask HN: How should I evaluate a startup as I job hunt?
You should (primarily) think like an investor. You are investing your time after all. For example, look at the questions that YC asks during interviews.

And then you have to think a lot more about the team/culture fit since you will spend way more time with the team than any investor.

jayzee··on Marc Andreessen Says Now's the Time to Build Companies Like It's 1999
That's what we are up to: Chemdex~=Quartzy

http://en.wikipedia.org/wiki/Chemdex.com

jayzee··on Referly Homepage Simplification Retrospective
I would recommend randomizing the initial condition for the images you are showing.

Right now you say 'items being referred now' but I refresh the page and it shows the same items sliding of the page again and again... Makes the activity on the site appear fake...

jayzee··on Should Applied Research Funding Go To Startups or Academia?
the post discusses funding for science-related startups broadly... including examples referring to academia.edu etc. i am responding to the contents of the post not just the title.
jayzee··on Should Applied Research Funding Go To Startups or Academia?
the later... support scientific research
jayzee··on Should Applied Research Funding Go To Startups or Academia?
This is a great post on a topic that is quite close to our hearts since we are a science-startup as well. I think that this situation is a symptom of the mentality, 'You can't be fired for buying IBM.' It is so much easier to give money to a research group at Harvard etc than 2 guys starting out from an apartment. Especially in a bureaucratic setting where your job is to make decisions that do not look bad, and not to actually make good decisions!

Adam and I were once on a call with an academic consortium that had received ~$15M in funding from ARAA. The objective of this group was quite similar to what we are doing with our startup. This group reached out to us too see if there was a way we could work together. During the conference call it was Adam and me on our side and at least 10 researchers from institutions all over the US on the other side!

Those were the early days of our startup and we thought that we would be obliterated by them with their vast resources. It turns out that with 1/10th their funding we have done more than 10x of what they did. And they are floundering while we are just warming up.

jayzee··on One Year, Six Products: What I’ve Built and Learned
Good post but surprised by his understanding of cash-flow positive: Being cash-flow positive is...when your costs not including salaries are lower than your revenues
jayzee··on You're not the CEO - You're the Fucking Janitor
In that case it would be nice if people would stop bashing janitors.
jayzee··on You're not the CEO - You're the Fucking Janitor
I did. The comparison seems to imply that being a CEO is not all that it's made out to be. It's like being the fucking janitor. Which is why I ask what is wrong with being a janitor.
jayzee··on You're not the CEO - You're the Fucking Janitor
What's wrong with being a janitor?
jayzee··on How we reduced our cancellation rate by 87.5%
Surely you see the difference between the two cases?
jayzee··on Why We Don't Believe in Science
True. I think that people who think that they are scientific like to believe certain things just as much as people who are not scientific. I am sure that if you sat Jonah down and asked him to prove any of these things there would be a squirt in his 'A.C.C.' circuit!
jayzee··on Why We Don't Believe in Science
I wonder why people hate on believing that the sun revolves around the earth. It would make for more complicated equations of motion, but is not unscientific or wrong to believe that to be the case. It just turns out that the math is easier when you believe that the sun is at the center.
jayzee··on Books Every Entrepreneur Should Read
Ok, follow-up post 13 days' after technology's recommendation. I got the book and I read it and I did not find the advice actionable. He interviews a bunch of vcs (and a few founders) but mostly vcs and you hear the same thing that you expect:

- Startups fail because they run out of money

- VC's like to invest in smart passionate entrepreneurs who are solving a personal problem who are not in it for the money.

- VC's like either big markets or great teams or both

- etc etc

Some of the interviews were great (Howard Morgan) but the problem with interviewing active vcs is that they can't talk about the stuff behind the scenes. Often founder's who have had successful exits have no such qualms.

jayzee··on I must be crazy
This comment is willfully ignorant.

Are you just upset that he is competing on price? Given his cost structure it makes perfect sense for him to want to deliver desirable projects for great customers at a great price.

Clearly you know that there is no fixed price that the market has decided professional iOS development is worth. And now that there is one additional professional iOS developer working from Vietnam the price turns out to be lower than what you think it should be.

jayzee··on San Francisco Tech Boom Brings Concerns
By the same token, rent-controlled apartments are unjust to the non-techies who are not in them.

To me it is plausible that the average price of an apartment would actually drop if they were no rent-controlled apartments. You would have more supply etc...

jayzee··on Paul Graham's Letter to YC Companies
So here is an idea for an email feature/gmail plugin: 'Semantic Scramble' Basically, any sensitive email that you send to a bunch of people is automatically scrambled (retaining original meaning/correct grammar, just a small shuffling of words) so that each person gets a unique email. Easy to find out who leaked it. You could add a similar unique jitter for sensitive photos/images...
jayzee··on For Tech Start-Ups, New York Has Increasing Allure
I think that the tech scene in nyc is anti-correlated with the stock market. I remember there was no activity when I was there and it started picking up post 2008 when the banks started laying off/stopped hiring technical people...

If the stock market picks up again I think that the tech scene will start receding. It is hard for quite a few people to turn down the pay that banks offer for the uncertain economic rewards of a startup.

jayzee··on Peter Thiel’s CS183: Startup - Class 14 Notes Essay
Mark Suster's blog, Both Sides of the Table
jayzee··on Books Every Entrepreneur Should Read
I always recommend Founders at Work to all my friends who are contemplating a start-up. Incredibly motivating stories!
jayzee··on After Facebook fails
Isn't this the same Michael Wolf that Loeb, the activist hedge fund manager, picked for Yahoo's board? If this is how he feels about businesses driven by online ads I wonder what he thinks of Yahoo's odds.
jayzee··on Gumroad raises $7 million from KPCB
The Samwer brothers don't seem to like waiting, and see the hell that they are getting.
jayzee··on Nobody Seems to Understand What Jeff Bezos is Doing. Does He?
please don't do the 'This' thing.
jayzee··on Turntable.fm: Where Did Our Love Go?
I got annoyed when I got into a disagreement with a moderator and was kicked out of a room repeatedly.

I am not sure how many others had a similar experience but I just left the site after that. It made the site feel unwelcoming.

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