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looofooo0

492 karma · joined January 24, 2024

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looofooo0··on Apple boss Tim Cook says prices to rise due to memory chip costs
most of it is near zero marginal cost.
looofooo0··on Apple boss Tim Cook says prices to rise due to memory chip costs
The iPhone is also a vehicle to hook people into the Apple ecosystem, where Services like the App Store bring in 40% of all gross profit with margins of 75%.
looofooo0··on Afroman found not liable in defamation case
https://www.youtube.com/watch?v=oponIfu5L3Y

This is the video in question, police again falling trap to the Streisand effect.

looofooo0··on Show HN: Scroll Wikipedia like TikTok
Graph structure of wiki could be exploited for user specific content.
looofooo0··on The biggest heat pumps
Its more this pesky flying things now.
looofooo0··on The biggest heat pumps
In Germany you have very strict laws for construction of water heating. For example the need to install thermostat on any heater even for floor heating. But this implies a lot of complexity for the heat pump installation. Cheap DIY community basically removes all the thermostats and soley controls heating through water temp and flow control to the radiators.
looofooo0··on The biggest heat pumps
Well that thing was never turned on in Germany.
looofooo0··on The biggest heat pumps
You mean if Germany still exists and the mongols did not have take over Europe.
looofooo0··on The biggest heat pumps
It was Philippsburg was 30km to Mannheim, Could have send 3GW of thermal energy over.
looofooo0··on The biggest heat pumps
1.6GWe gives you 3.2GWt max alongside. In more modern this is even less. Of the 100% energy produced 33-38% will end up in the electric grid.
looofooo0··on The biggest heat pumps
I was solely talking about heat pump adoption due end user prices.
looofooo0··on The biggest heat pumps
No, this is a lie. It is also funny because Germany was so depended on Russian Gas that nuclear fuel even if fully depend on would be laughable.

Germany has its own fuel enrichment and production, and it is still running https://de.wikipedia.org/wiki/Urananreicherungsanlage_Gronau

And no Uranium ore does not stem from Russia, they might still produce some of the UF6, but this can be much more easily shifted because unclear fuel cost are only a small fraction of the total cost!

looofooo0··on The biggest heat pumps
Well in the south you might need to factor the gas cost in (vs Germany) and also the network effects of heat pump being the main form of heating in sweden.
looofooo0··on The biggest heat pumps
Germany at its best, instead of keeping its 20GW+ nuclear power running and get district heating pipes installed to them, they engineer this solution at x times the cost. In this case a 30km pipe from Philippsburg NPP would have done the trick.
looofooo0··on The biggest heat pumps
Well Norway (Hydro), Sweden (hydro and nuclear) and Finland (Nuclear Wind Hydro) all have cheap electricity which seems to be the main driver for adoption.
looofooo0··on Voyager 1 is about to reach one light-day from Earth
Class 1 civilization has a lot of resources
looofooo0··on Voyager 1 is about to reach one light-day from Earth
Americium battery could last a lot longer.
looofooo0··on Germany to ban Huawei from future 6G network
I do Openwrt on my HP
looofooo0··on Solarpunk is happening in Africa
500wh battery can deliver that for 1 hour.
looofooo0··on Solarpunk is happening in Africa
So? Everyone used to cook over woodfire. If the benefits are good enough, like massiv time saving, it will change.
looofooo0··on Solarpunk is happening in Africa
Not really, my old microwave has 500 Watts, this should be also enough for slow resistive cooking while being insulated.You will find 12V/24V 2.8L/5L Dc Electric Pressures Cookers with 250W-300W on AliExpress. (1l needs roughly 0.1kwh of energy to go from 20 to 100°C) Additionally, you might save a lot of energy by using a hay box after it starts to boil. https://en.wikipedia.org/wiki/Haybox
looofooo0··on Solarpunk is happening in Africa
alibaba.com/product-detail/Solar-DC-12V-24V-Battery-Powered_60758353185.html
looofooo0··on Solarpunk is happening in Africa
Laptops, TVs and other electronics already run from DC. Also, there are a lot of appliances for camper vans, boat which run on 12v or 24v DC. On Alibaba you can buy a stove for a few bucks: https://www.alibaba.com/product-detail/Solar-DC-12V-24V-Batt...
looofooo0··on We're losing the war against drug-resistant infections faster than we thought
Well Phage guard and similar products using a replacement schedule and many phages in one cocktail. But this does not mean that page guard like products would not be successfully as medicine, but as a medicine this is not possible as it is non-stable and containing live viruses. At best, you would need to get a new approvable every time the cocktail changes.
looofooo0··on We're losing the war against drug-resistant infections faster than we thought
Phages are binding to very specific proteins, where as antibiotics disrupt more fundamental processes.

Personal medicine as in individual combination of existing drugs is easier to achieve in current regulatory framework then using new drugs.

looofooo0··on We're losing the war against drug-resistant infections faster than we thought
Much slower, we are still using 100 year old antibiotics. Money one phage is going to make is much smaller. This is not cost effective to go through the whole process.
looofooo0··on We're losing the war against drug-resistant infections faster than we thought
They are only active against a narrow strain of bacteria unlike antibiotics.
looofooo0··on We're losing the war against drug-resistant infections faster than we thought
I don't understand your point? The only thing I said that the process of developing new medicine is ill-suited for phage treatment. This due the fact bacteria and phages are coevolving, hence any phage treatment is highly specific and hence not worth of developing. It needs new ideas to standardize the process and to make this process a legal treatment option.
looofooo0··on We're losing the war against drug-resistant infections faster than we thought
"we found some adverse events associated with phage therapy, but serious events were extremely rare."

The biggest hindrance is that the western process of developing and releasing new medicine is ill-suited for phage treatment.

looofooo0··on We're losing the war against drug-resistant infections faster than we thought
George Eliava Institute in Tbilisi is where you could get such a treatment. In the West you might be able to source it from food production related suppliers: https://phageguard.com. I guess an open wound where treatment with antibiotics fails and loosing your foot etc. is on the table, this might be an option of last resort.
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