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maksimilian

15 karma · joined November 1, 2017

https://digitalbio.org/
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maksimilian··on Caving scientists exploring the darkest places on Earth
Oh wow - I saw this story a few weeks ago (absolutely horrifying) and ended up binging on caving incident stories. My takeaway was that regardless of how experienced the spelunkers are, something can go wrong.

In the midst of my binge, I also found this awesome(ly horrifying) Youtube Channel of cave explorers. They have explored some amazing caves, but here's a video of them in some really tight spaces to illustrate the risk these explorers take (warning, may induced some anxiety): https://youtu.be/Us-XA2BRLgg?si=Lb62ZE1IHG4MD6K3&t=677

maksimilian··on Finding Bio-Software Fit
A product primer for entrepreneurs working at the intersection of technology and biology.
maksimilian··on Is technology harming our brains?
I enjoyed the ending of your ending.

It is not only the fact that we are getting mentally lazy by having on demand access to all of human knowledge and opinion, but it is also that it takes the magic out of certain social interactions. For example, having a discussion with a friend over coffee, where both of you might be trying to remember the details of a specific topic. Previously, you might have spent 10-15 minutes digging into the topic, exercising each other's memory until you both arrived at the 'aha' moment where suddenly you remember the key detail/fact that you both were looking for. Anecdotally, when that happened, it was a deeply rewarding moment (dopamine hit, but you had to work for it!). With all of this knowledge at our fingertips, those moments are gone. I wonder if the lack of that mental 'sparring' and the ensuing reward that it brings is causing us to miss out on a key social/mental feedback loop that could not only allow you to exercise your mind, but also to get you used to moments of frustration and disagreement with another person (which is a useful skill to develop when you are contending with someone on a topic in which the answer is unknown).

Anyway, more relevant to the parent comment, we have faced this challenge before in the physical domain (i.e. our ability to move ourselves vs transportation technology). We have bikes, cars, trains, and planes (and now cybertrucks!), yet we still recognize the necessity for physical exercise (although Ozempic and other weight loss drugs may change this dynamic). Ultimately, with the introduction of technology that makes our lives easier (at least initially), the natural capabilities that we've developed over billions of years to serve those functions become vestigial if not used.

maksimilian··on Ask HN: Where to meet non-technical cofounders?
what kind of projects are you working on? or what do you want to be working on?
maksimilian··on At 31, I have just weeks to live. Here's what I want to pass on
It is ok to show a little humanity once in while...even on HN
maksimilian··on Let’s avoid talk of ‘chemical imbalance’: it’s people in distress
You should check out this company studying the gut brain axis :)

https://www.kallyope.com/

maksimilian··on Limitations and pitfalls of the job interview
I imagine a good compromise might be a small piece of "contract work" where a company presents a small representative task as a project for a candidate to complete and the candidate actually gets some form of compensation for their time. There are definitely problems to this approach, but in a best case scenario, the result is a win-win situation even if a candidate doesn't get hired. At the moment every candidate that doesn't get hired represents a net loss for both parties (time for both and opportunity for the candidate)
maksimilian··on Founder-driven life sciences companies
If you are interested, I can connect you with a consultant in the field who works with VCs and young biotechs. Really great to work with and if he can't help you out, I am sure he knows someone who can help you.
maksimilian··on How pharmaceutical industry financial modelers think about rare diseases
Weren't these things already public knowledge? Did the pharma folks just dislike that you made it easily accessible?

How do you make money off of DrugBank now?

maksimilian··on Ask HN: What is your money-making side project outside programming?
As someone who records in their spare time, would you mind sharing the progression of how it grew from a hobby to a business/side gig?
maksimilian··on Business networking is overrated (2017)
Do you have any examples? Or can you explain how exactly it would work to make these connecting people financially lucrative?