Of course, the current administration has shown quite a disregard for the rule of law to date, so I wouldn't put it past them to change the rule or apply the rule inappropriately to punish individuals who are critical of policy.
2,147 karma · joined March 11, 2015
Of course, the current administration has shown quite a disregard for the rule of law to date, so I wouldn't put it past them to change the rule or apply the rule inappropriately to punish individuals who are critical of policy.
Ringbauer, H., Salman-Minkov, A., Regev, D. et al. Punic people were genetically diverse with almost no Levantine ancestors. Nature (2025). https://doi.org/10.1038/s41586-025-08913-3
https://www.nytimes.com/2025/04/22/science/trump-national-sc...
The paper referenced:
J.A.M. Erven, V. Mattiangeli, M. Dreshaj, V.E. Mullin, C. Rossi, K.G. Daly, I. Jackson, M. Parker Pearson, D.G. Bradley, L.A.F. Frantz, O. Madsen, D. Raemaekers, & C. Çakirlar,
Archaeogenomic insights into commensalism and regional variation in pig management in Neolithic northwest Europe, Proc. Natl. Acad. Sci. U.S.A. 122 (12) e2410235122, https://doi.org/10.1073/pnas.2410235122 (2025).More analysis here: https://www.nytimes.com/2025/04/22/us/politics/university-le...
• Trump Laid Off Nearly All the Federal Workers Who Investigate Firefighter Deaths -- https://www.propublica.org/article/trump-cuts-firefighter-de...
> National Institute for Occupational Safety and Health, will also halt a first-of-its-kind study of the causes of thousands of firefighters’ cancer cases.
https://news.ycombinator.com/item?id=43653605
The proposed cuts, if enacted, will devestate scientific research at NASA (50% cut to science programs).
For me at least, the "bundle" is basically all the clothing that will be used at my destination.
Like any other packing situation, you'd keep a jacket, sweater, headphones, etc. outside of the bundle for easy access en route.
https://www.aphis.usda.gov/livestock-poultry-disease/avian/a...
• Choose "Total Outbreak" in the site above to see the full breakdown across states
The USDA's own website has the following headline text:
"Testing for HPAI H5N1 is crucial to achieve disease freedom from this virus in U.S. dairy cattle. USDA works closely with Federal, State, and industry partners to ensure our testing activities are comprehensive. "
https://www.aphis.usda.gov/livestock-poultry-disease/avian/a...
I guess the USDA and FDA are failing to communicate with each other.
https://apnews.com/article/texas-measles-outbreak-rfk-jr-ben...
• NIH bans all future grants to universities with DEI programs or Israel boycotts -- https://www.statnews.com/2025/04/21/trump-nih-grants-draft-r...
• NIH freezes funds to Harvard and four other universities, but can't tell them -- https://www.science.org/content/article/nih-freezes-funds-ha...
https://www.reuters.com/world/scientists-us-harried-by-trump...
https://www.seattletimes.com/business/more-americans-are-eye...
https://www.cbsnews.com/news/fda-food-safety-inspections-pla...
Having run across it ~20 years ago, I still use their recommended "bundle wrapping" (https://www.onebag.com/pack.html) technique when I need to pack efficiently.
The current administrations security track record to date is less than stellar, as evidenced by recent DoD/Pentagon lapses. It's hard to have any confidence that a rushed job from HHS will be any better implemented.
"A bill for an act relating to public safety; designating mRNA injections and products as weapons of mass destruction; prohibiting mRNA injections and products; proposing coding for new law in Minnesota Statutes, chapter 609."
Schwartz MA. The importance of stupidity in scientific research. J Cell Sci. 2008 Jun 1;121(11):1771. doi: 10.1242/jcs.033340. PMID: 18492790. -- https://journals.biologists.com/jcs/article/121/11/1771/3003...
https://grants.nih.gov/grants/guide/notice-files/NOT-OD-25-0...
Yes, machine learning/AI is powerful, but pie in the sky predictions such as the "end of disease" probably hurt more than help in the long run.
Trump can seem to help himself with respect to making pronouncements / fueling speculation that inevitably drives the markets down.
The actual letter (link included in article above)
-- https://www.documentcloud.org/documents/25900701-chest-doj-l...
However, your points 1, 2, and 4 unfortunately don't apply well to anti-fungals.
* "There is limited evidence that farming use of [anti-fungals] is what drives resistance in clinical cases."
Certainly not the case with respect to azoles:
-- Rhodes J, et al. Population genomics confirms acquisition of drug-resistant Aspergillus fumigatus infection by humans from the environment. Nat Microbiol. 2022 May;7(5):663-674. doi: 10.1038/s41564-022-01091-2. Epub 2022 Apr 25. Erratum in: Nat Microbiol. 2022 Nov;7(11):1944. doi: 10.1038/s41564-022-01160-6. PMID: 35469019; PMCID: PMC9064804. https://pubmed.ncbi.nlm.nih.gov/35469019/
-- Celia-Sanchez BN, Mangum B, Gómez Londoño LF, Wang C, Shuman B, Brewer MT, Momany M. Pan-azole- and multi-fungicide-resistant Aspergillus fumigatus is widespread in the United States. Appl Environ Microbiol. 2024 Apr 17;90(4):e0178223. doi: 10.1128/aem.01782-23. Epub 2024 Apr 1. PMID: 38557086; PMCID: PMC11022549.
-- Impact of the use of azole fungicides, other than as human medicines, on the development of azole‐resistant Aspergillus spp. https://www.efsa.europa.eu/en/efsajournal/pub/9200
"* There is no reason to believe we've hit a wall and can't invent more antibiotics in the future. "
-- There are very few anti-fungals, because fungi, being eukaryotes, have cell biology so close to ours. The "big three" are 1) azoles (lots of resistance; see above); 2) echinocandins; and 3) amphotericin B (highly toxic to the host)
-- One bright spot is a new antifungal published a few weeks ago in Nature, called Mandimycin: https://www.nature.com/articles/d41586-025-00801-0
* "There are still some antimicrobial treatment techniques we haven't put a lot of resources in. Like, bacteriophage treatments, or cycling antibiotics."
-- Bacteriophage don't work on fungi. Some degree of cycling and combination anti-fungal treatment are already in use.