puzzlingcaptcha

"But if we don't engineer addiction, China will beat us to it! It's a national interest!"

Thanks, I'll just keep using XMPP MUCs like a caveman I am.

HSALF backwards reads FLASH but Sir68k is just a very diligent guy.

Crop futures are already a thing. Potatoes are traded on EEX for example: https://www.eex.com/en/markets/agriculturals/potatoes

I'm not a Mac user, but ever since Google changed their icons a couple years back I still struggle to tell apart Maps/Photos/Drive etc at a glance.

You can easily tell UX design roles are obsolete by the recent threads about Tahoe and W11. There is going to be whiplash.

Is NanoVNA still the best entry-level tool in 2026?

I have my own travel story involving DB. I had a ticket for a Lufthansa flight from Frankfurt am Main to Warsaw. When I tried to check-in online a day before the flight it told me I had to do it at the airport. I fly a bit, so I knew what that meant - they overbooked the flight. The next day I got my "no aircraft entry guaranteed" boarding card of shame at the airport and learned at the gate that they overbooked the plane by three persons! After explaining my EU passenger rights, I got them to confirm my €250 compensation and since I was in an adventurous mood headed for the Frankfurt Flughafen Fernbahnhof train station.

The manned DB Travelcenter was still open so I walked in and asked for an international ticket to Warsaw. The gentleman (who spoke fluent English) typed a bit on the computer and told me he cannot sell a ticket for the Berlin-Warsaw leg of the journey due to a "system error on the Polish side". I knew that probably meant the Berlin-Warsaw-Express is at full capacity again and they don't sell tickets with no seat indicated for that route. I asked for a ticket to Berlin instead (€207, 2nd class) and went for a hamburger - still had about an hour until the train.

The train was initially supposed to arrive delayed 5 minutes but that was soon to change. The delay kept ticking up to 20 minutes, 45 minutes, 1 hour (around this time the DB travelcenter closed for the night) then two hours then cancelled altogether. I wasn't sure if my ticket is valid for the next train (the DB website was a bit vague about that) so I called my friend in Hamburg who confirmed I was good to jump onto the next train which would arrive on schedule in another three hours. I tried getting a Capri-Sun from a vending machine but it got stuck and wouldn't fall out. So I sat at the empty station with noting but rats as company until 3AM when the next Berlin-bound train arrived on time. In Berlin I got out at Sudkreutz and jumped onto a FlixBus to Poznań (€22) and stayed the night over at my friend's place (I badly needed a shower at that point) before taking a train to Warsaw the next day (€16, 2nd class).

Now, I technically did eventually use my Frankfurt-Berlin ticket but I was quite annoyed at DB so I applied for a reimbursement due to a cancelled train, which was granted in full. I also applied for reimbursement of the plane ticket from Lufthansa which was also granted. With the additional €250 compensation for denied boarding I actually made money on that little adventure but I probably wouldn't do that again. Gotta check in earlier from now on.

I wish AVR DU series had any sort of open source support, we could finally move on from 32U4.

https://www.microchip.com/en-us/products/microcontrollers/8-...

I think people have a wrong idea of what a modern atomic clock looks like. These are readily available commercially, Microchip for example will happily sell you hydrogen, cesium or rubidium atomic clocks. Hydrogen masers are rather unwieldy, but you can get a rubidium clock in a 1U format and cesium ones are not much bigger. I think their cesium freq standards are formerly a HP business they acquired.

Example: https://www.microchip.com/en-us/products/clock-and-timing/co...

that's just unchecked neurotoxoplasmosis

I guess you could say that MiniDisc was the original HAMR format.

The second part of the article is right here: https://blog.genesmindsmachines.com/p/python-is-not-a-great-...

The 'sequel' is also online: https://blog.genesmindsmachines.com/p/python-is-not-a-great-...

01005? Oh no no no. I can barely do 0402s by hand and those are _2.5x_ larger.

For those who missed out: you could end up in a shotgun wedding then get a divorce in New Reno, Las Vegas-style.

7400 clocks at 1.1 GHz so it's not really it. 7600m is what it looks like.

For 800 eur I'd rather get the cheaper Framework desktop motherboard (Ryzen AI 385) and build around that.

It sort of depends on what you perceive as 'high'. Many TVs have a special low-latency "game" display mode. My LG OLED does, and it's a 2021 model. But OLED in general (in a PC monitor as well) is going to have higher latency than IPS for example, regardless of input delay.

It's not unusual to feel good after pulling an all-nighter. Sleep is when re-uptake of serotonin takes place, so if you interrupt it you end up with a surplus. Although there are also other possible explanations [1]

1. https://www.pnas.org/doi/10.1073/pnas.2214505120

I'm going to add:

4) The penny-pinching RPi does on hardware: be it RTC, usb power kerfuffle or ARM crypto extensions (finally added in Pi 5)

5) accessory lock-down: see the situation with Pi cameras, or better yet DSI displays (CM4 datasheet: Although Linux kernel drivers are available, the DSI interface is not currently documented. Only DSI displays supported by the official Raspberry Pi firmware are supported.)

6) half-assed documentation (if you know, you know)

7) the ever-present marketing to compensate for the previous points, and the fact that it works

This is exacerbated by its popularity so people tend to treat raspberry pi as a hammer for all of their nails, while in many cases a 2$ mcu would suffice or a more network-capable SoC would be a much better fit (raspberry Pi NAS, pihole etc).

X Elite does not have AVX instructions (they are emulated instead)

from the article:

>Many of the problems with yaml are caused by unquoted things that look like strings but behave differently. This is easy to avoid: always quote all strings.

Sometime around 2015 I promised myself to never buy a laptop with switchable graphics again. This has worked well so far.

But it never ceases to amuse me watching brands that position themselves as 'premium' spending pennies on firmware development team somewhere down in a basement compared to millions they spend on shiny marketing.

Raspberry Pi Foundation failing to communicate their development of this stepping will results in tens of thousands recently bought A2-stepping devices ending up in the landfill.

The uridine modification was intended to reduce immunogenicity of mRNA - some of our immune cells have pattern-seeking receptors in the TLR family that recognize ssRNA and dsRNA. The presence of modified uridines throws this pattern recognition off. (https://doi.org/10.1016/j.jconrel.2015.08.051)

The modifications to increase mRNA half-life concerned mostly the caps and poly(A) tail. But even with those the persistence was in the range of days (sort of depending on how sensitive a method you picked).

AAV based therapies may have no permanent effect when the cells in question are actively proliferating (and the payload dilutes with each division) but muscle tissue is largely post-mitotic.

mRNA is in comparison very transient (in the range of days, and that's being charitable), even when modified (5' cap, uridine analogs, poly(A) tail) as it was in COVID vaccines. This is fine for vaccines, as you essentially want just a single exposure to the protein with each vaccine dose. You do need dystrophin continuously though (even though the cells are not dividing much, they are still recycling it).

You could argue for delivering gene therapy with mRNA/NLPs in multiple doses over the course of patient's life but that would likely 1) exacerbate toxicity and 2) be super-expensive

AAV-based vectors are specifically non-integrating. Wild-type AAVs can integrate, but in the absence of rep protein they will instead persist in the cell nucleus in the form of episomal concatemers - long, circular DNA structures containing multiple copies of the virus DNA. These will not replicate when a cell proliferates - they will instead dilute with each division. This makes them desirable for treating diseases affecting post-mitotic tissue like muscle, less so for, say, bone marrow. Unless transient expression (but not as transient as with NLPs) is what you want.

If you can do without SPI there's also https://www.adafruit.com/product/4471 You can also just get the chip (MCP2221A) in a DIP package and just pluck it in a breadboard. All you need is two bypass caps and two pullup resistors if you need I2C.

You can still buy a new subcompact car (like a Renault Clio or Skoda Fabia) in Europe for under 20k EUR.

The more interesting question is why these cars disappeared in the US. And while many of the factors discussed here are true for both EU and US (inflation, interest rates, manufacturer profit margins etc) I am surprised no one mentioned the 'SUV loophole' of US regulations that effectively boosted the SUVs (off-road vehicles are classified as non-passenger automobiles with everything that entails, notably much less stringent emission standards) and made the small cars unprofitable to make in comparison.