161 karma · joined May 19, 2020
The Maya and Aztec had writing in the form of hieroglypics. The Inca had persistent communication via Quipu's rope knots.
(I learned this from _Guns, Germs, and Steel_ which is a phenomenal book. I haven't done other research, though, so maybe the book isn't a good source.)
Using "something" to manipulate the donor cells has also been done for these autologous HSCTs. I know of "CAR T cell therapy", but there are likely others. ( https://www.cancer.gov/about-cancer/treatment/research/car-t... )
I think some small number of autologous HSCT recipients require immunosuppressants, but from what I remember the number is very very small. (Allogenic HSCT recipients, who receive cells from a different person, are _much_ more likely to require lifetime immunosuppressants.)
It's super cool that they're able to treat genetic diseases this way!
I haven't done this in probably 7 years, though. Mostly because I haven't cultivated this kind of working relationship with my coworkers.
Some of those behaviors are generally for the good of society (e.g. 'murder is bad'). But others, like civil forfeiture, are much much more questionable.
If you have full-disk-encryption and a crypto-wallet passphrase, you may be held on contempt charges anyways. That might be better, it might not. The underlying problem of "the state can seize your assets if you act 'suspicious'" is still there.
In this hypothetical, I don't believe I did anything explicitly wrong. But I also didn't handle the situation well. Maybe the "sorry" is "sorry for not addressing your concern". Or maybe it's just "sorry that 'mansplaining' is a situation you encounter frequently". It doesn't have to be BLAME. Just empathy.
This makes me sad, but it is exactly what I would have done. My life is built on avoiding anything awkward or uncomfortable. And...that's not working for me anymore. Thanks to a mental health professional, I'm working on embracing these "problems".
If I had your experience today, I'd come up with a plan to at least clarify things. I'd probably start with a slack message. Maybe something like:
> I'm sorry.
> When I talk programming puzzles with <person>, we have a routine of the first person to solve waits a short while and then shares the answer.
> I like that system, as spending 45 minutes to come up with the "trick" usually isn't fun for me.
And then see how the conversation goes. I'd expect 70% something with the feeling of apology-accepted, 20% being told that mansplaining is a pattern of mine, 5% things getting very personal/real/vulnerable, and 5% wildcard. Maybe the estimates are wildly off. I'm still new to being honest and real. But today-me looks at those odds and says sum of awkward + fear isn't high enough to beat the expected value of the conversation.
I don't think this is precisely correct. In the situations like in the article, the issue is that both parties are playing a dance around _what kind of feedback/criticism_ is acceptable.
If I ask you "why might my business fail?", and your gut reaction is "your personal life is a mess", do you tell me this? Even with an NDA, that's _super harsh_ feedback.
(This feedback would hurt me more AFTER the NDA. The NDA would change my expectations around the types of feedback. I'd expect "you're not a good programmer" or "you don't work enough hours to beat the competition".)
But if I _really_ wanted to have my business succeed, that's feedback I probably need from someone other than my therapist. :)
As a one-off (or a personal "hack"), the NDA is an offering of empathy. Sharing sincere feedback is hard. Offering the NDA shows that the advice-asker is worried about the advice-giver's well-being. It's nice and genuine, and I hope it will work.
But, this idea seems so GOOD at first blush, that I'm afraid it will become widespread and lose sincerity. Anytime feedback is involved, the NDA appears as legal boilerplate. It's no longer a personal connection built on shared vulnerability. Instead, it's a corporate threat: "If you want advice, we can either be friends or go to court."
Measuring one-way speed of light requires perfectly synchronized clocks. You cannot do this over any distance, as it requires the speed of light to propagate between the clocks. So you must synchronize the clocks when they are together.
But then you must move at least one clock, which subjects the clocks to unknown time dilation. We can't even assume that the time dilation from movement X is the same as from movement -X, even to impossibly-precise measurements and controls. The _premise_ of the question about one-way speed of light is un-divorceable from time dilation. If you _assume_ that the time dilation is the exact same, you are also _assuming_ that the amount of time light takes from A-to-B is exactly half of A-to-B-to-A.
Einstein himself articulated this problem. He's certainly known for more than "attempting to be a physicist".
I don't know of any way to prove feeling. It seems like a solipsistic trap. I _believe_ that most animals "feel", and _believe_ that no plants/fungus do...but it is merely belief that I don't think to be testable.
Additionally, although oysters (and at least dozens of other species of animals) lack a CNS, they also react to external stimuli. In fact, oysters are used in some water systems as sophisticated water quality detectors, e.g. in San Diego https://www.youtube.com/watch?v=UJJz15N1KEY .
I expect the federal government to take action here, probably by giving huge monetary incentives to Intel/AMD for creating a state-of-the-art fab in the US.
would it change the legal perspective? I could totally see myself seeing such an email and making decisions based on the premise that I had additional income coming. I think I've read advice in the past that if a "reasonable person" would believe it, then it counts as an informal contract or something.
My company used to mandate all emails are signed with AD-registered certificates to lend credibility, but they've moved away from that. (I think the reasoning was that webmail clients don't have robust support for S/MIME certs, but I'm not sure.)