Hacker News Reader

robbseatonon Google suspending Parler from the Google Play store

More than 200 BLM protests turned violent.

https://acleddata.com/2020/09/03/demonstrations-political-vi...

robbseatonon Ask HN: Has anyone fixed their own bruxism?

Try magnesium.

robbseatonon A Nearly Extinct Bootlegger's Corn Gets a Second Shot (2018)

Hey, I love to trade seeds! I've got all sort of hot peppers. E-mail me at robb at rs dot io ? Other HNers welcome, too.

robbseatonon Japan set to ban entry from the U.S. as early as next week

Previous experience with SARS is a better candidate for "primary determiner."

robbseatonon Crystal 0.33

n=1 but I am a Rubyist migrating to Julia, FWIW.

robbseatonon ThinkPad Mods, Done Right

http://www.cnmod.cn/

robbseatonon FDA Approving Drugs at Breakneck Speed, Raising Alarm

Is the FDA Too Conservative or Too Aggressive?: A Bayesian Decision Analysis of Clinical Trial Design

The results for conventional fixed-sample randomized clinical-trial designs suggest that for terminal illnesses with no existing therapies such as pancreatic cancer, the standard threshold of 2.5% is substantially more conservative than the BDA-optimal threshold of 27.9%. However, for relatively less deadly conditions such as prostate cancer, 2.5% is more risk-tolerant or aggressive than the BDA-optimal threshold of 1.2%. We compute BDA-optimal sizes for 25 of the most lethal diseases and show how a BDA-informed approval process can incorporate all stakeholders’ views in a systematic, transparent, internally consistent, and repeatable manner.

https://www.nber.org/papers/w21499