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tuxguy

1,269 karma · joined March 16, 2011

Passionate about python, ml & bioinformatics. I nerd about how tech & ml will impact medicine broadly, especially cancer & rare diseases.

I am very active on twitter : twitter.com/acgt01 DMs open

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tuxguy··on Desert Ant Labs: local, fast models that run on device
brilliant ! Would love to see a deep dive on your component design system & copy process.

Here is to more beauty in the world - both physical & digital :)

tuxguy··on I used Claude Code to get a second opinion on my MRI
there is often discordance between radiologists(& doctors in general) when reading the same scan(same case vignette) as well !
tuxguy··on Ask HN: Share your personal website
https://inventcures.github.io/
tuxguy··on alphaXiv: Open research discussion on top of arXiv
awesome honking idea ! please add "spaces" for biorxiv and medrxiv too !
tuxguy··on Everyone hates the electronic medical record
what about openehr [0,1]

it is fairly popular in europe. What is required for federal certification ?

0. https://openehr.org/ 1. https://openehr.org/products_tools/platform/

tuxguy··on Details emerge of surprise board coup that ousted CEO Sam Altman at OpenAI
An optimistic perspective of how despite today's regrettable events, Sama and gdb will start something new and more competition is a good thing : https://x.com/DrJimFan/status/1725916938281627666?s=20

I have a contrarian prediction : Due to pressure from investors and a lawsuit against the openai board, the board will be made to resign and Sama & Greg will return to openai.

Anybody else agree ?

tuxguy··on Azure ChatGPT: Private and secure ChatGPT for internal enterprise use
The linked github repo was active yesterday and is now returning a 404.

anybody know why ?

tuxguy··on Malignant melanoma deploys elegant molecular mechanism to evade immune responses
the paper by ben izar et al :

https://www.sciencedirect.com/science/article/abs/pii/S15356...

tuxguy··on Stack overflow launches overflow AI [video]
more info at https://stackoverflow.co/labs/
tuxguy··on Inside the Wuhan lab weeks before Covid
non-paywall version : https://archive.md/Edw0k
tuxguy··on Gilbert Strang's final lecture at MIT: May 15, 11:00am
one related quote i really like is : "it takes a lot of knowledge to realize the extent of your own ignorance" :D
tuxguy··on Gilbert Strang's final lecture at MIT: May 15, 11:00am
comments like these keep make me coming back to hn :) witty comments ftw !
tuxguy··on Diagnosing cancer by profiling the immune system
Thanks for this reminder about Pieter Hintjens. I have been greatly influenced by his writing, including his use of Alice & Bob, in "a protocol for dying" ! So witty, so clever - such a tragic loss.
tuxguy··on ChatGPT could cost over $700k per day to operate
"“I think we’re at the end of the era where it’s gonna be these giant models, and we’ll make them better in other ways,” Altman said.

He sees size as a false measurement of model quality and compares it to the chip speed races we used to see. “I think there’s been way too much focus on parameter count, maybe parameter count will trend up for sure. But this reminds me a lot of the gigahertz race in chips in the 1990s and 2000s, where everybody was trying to point to a big number,” Altman said.

As he points out, today we have much more powerful chips running our iPhones, yet we have no idea for the most part how fast they are, only that they do the job well. “I think it’s important that what we keep the focus on is rapidly increasing capability. And if there’s some reason that parameter count should decrease over time, or we should have multiple models working together, each of which are smaller, we would do that. What we want to deliver to the world is the most capable and useful and safe models. We are not here to jerk ourselves off about parameter count,” he said."

via https://techcrunch.com/2023/04/14/sam-altman-size-of-llms-wo...

tuxguy··on After cancer diagnosis, neurosurgeon sees life, death and career in a new way
loved this, thanks for sharing !
tuxguy··on Launch HN: Medplum (YC S22) – Open-Source Firebase for Healthcare
Congratulations team medplum. Sounds really neat !
tuxguy··on CS109a: Introduction to Data Science – Resources
Couldn’t find videos. Anybody have luck with that ?
tuxguy··on Ask HN: Burnt-out, directionless but want to turn it around
Also checkout recurse centre. https://www.recurse.com/about
tuxguy··on Ask HN: It's 2022. Where should I direct the youths to learn about programming?
came here to recommend cs50 and david malan ! one of the best cs teachers, who really cares about teaching !
tuxguy··on Drones have transformed blood delivery in Rwanda
paywall free version https://archive.md/pbYBZ
tuxguy··on Algorithms for Decision Making [pdf]
May be a little OT but came across this technique called MABs multi armed bandits , related to , finding optimal ways to decide among a sequence of actions and measuring their utility

https://en.m.wikipedia.org/wiki/Multi-armed_bandit

Has applications in a wide variety of fields : optimal design of clinical trials, public policy decision making.

apparently has some relation to the work abhijit banerjee & esther duflo, the nobel prize winning economist couple have done on design of experiments, to measure impact of developmental interventions

tuxguy··on Why is selling software so weird?
Fantastic read ! I have never had leverage explained so simply and succintly .

The author really has a gift for great articulation.

tuxguy··on Ask HN: How to improve as a struggling junior software engineer?
Hang in there. You are being too hard on yourself.

Most of us have gone through some version of this at some point in our lives, so take a breath and cut yourself some slack.

Lots of great advice on this thread already, so I will live it there.

tuxguy··on Andrew Ng: Unbiggen AI
lol-ing at "Whatever ml is pretending to be this week"

so funny, because so accurate :)

tuxguy··on I decided that I must live my life on my terms
sorry to hear that, i hope if you feel like working a job again, you find kind, compassionate coworkers.

Our experience of interviewing & working is a function of the people we interact with and there are both "good" and "bad" people. I have experienced both during my career and i hope, i ( & everyone else) gets to experience more of the "good" ones !

tuxguy··on Ask HN: How to raise funds for rare disease research?
https://www.statnews.com/2018/10/22/a-tailor-made-therapy-ma...
tuxguy··on Ask HN: How to raise funds for rare disease research?
please check out Perlara and Ethan Perlstein

https://twitter.com/eperlste?lang=en

tuxguy··on Magit, the magical Git interface (2017)
Noob question : is magit only for Emacs users ?
tuxguy··on “Pay for success” contracts – a model to develop new therapies from old drugs
Insightful discussion !
tuxguy··on Launch YC S21: Meet the Batch, Thread #8
What a neat story ! Congratulations and all the best Are you hiring ? :)
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