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uptownfunk

2,125 karma · joined May 12, 2015

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uptownfunk··on Binius: Highly efficient proofs over binary fields
Wow great article, I like the recaps
uptownfunk··on Is finding gaps just hard now? As a 24 yo, everything seems to be done already
It’s not about gaps it’s about value
uptownfunk··on AlphaFold 3 predicts the structure and interactions of life's molecules
You know I can appreciate that. For some reason because it’s related to medicine, it feels insidious to keep it closed.
uptownfunk··on AlphaFold 3 predicts the structure and interactions of life's molecules
The risks don't exceed what is already out there. If someone wants to do damage, especially in America, there are more than enough ways they can do it already. The technology should be made free. I also wonder how much the claims are being exaggerated and are marketing-speak vs. real results. Is there any benchmark for this that they have published?
uptownfunk··on AlphaFold 3 predicts the structure and interactions of life's molecules
Very sad to see they did not make it open source. When you have a technology that has the potential to be a gateway for drug development, to the cures of new diseases, and instead you choose to make it closed, it is a very huge disservice to the community at large. Sure, release your own product alongside it, but making it closed source does not help the scientific community upon which all these innovations were built. Especially if you have lost a loved one to a disease which this technology will one day be able to create cures for, it is very disappointing.
uptownfunk··on Ask HN: What nonfiction books do you keep rereading?
The Rama Charit Manasa

Bhagavatam

Bhagavad Gita

Chaitanya Caritamrta

Mahabharata

uptownfunk··on Ask HN: What nonfiction books do you keep rereading?
One of the best. So much wisdom. I try to read a chapter a day. Amazing.
uptownfunk··on Vets fret as private equity snaps up clinics, pet care companies
Why are you being downvoted? Firms regularly to saddle up the portco with debt and then completely gut and reorg the business and flip it up, that’s the model
uptownfunk··on Show HN: SpRAG – Open-source RAG implementation for challenging real-world tasks
Uh, isn’t there a huge venture backed startup that rhymes with spleen that contradicts this? Not saying you’re wrong but.. one of you is.
uptownfunk··on Cardio fitness is a strong, consistent predictor of morbidity and mortality
Regardless of what it is, if I don’t get my morning run in, I am a very unpleasant person to be around! Running has changed my life in all ways- I am much more calm, tolerant, positive, energetic. If the whole country did a mandated morning run, assuming you’re able, I really think this world would be a much better place!!

Start slow, 5 minutes, breathe, go slow, and enjoy the beautiful weather here this time of year.

uptownfunk··on Ask HN: My brain is telling me to quit everything. What should I do?
There are these things called Golden Teachers that can give you a great reset on life. You have a lot of trauma and you need to heal yourself through it. assuming you don’t have a family history of schizophrenia you may want to consider finding the golden teachers
uptownfunk··on Starbucks shares sink 8% as same-store sales fall, quarterly results miss
I can’t afford it

I want something with organic milk and ideally organic beans

I want better quality pastry

uptownfunk··on The man who killed Google Search?
Oh how I would love to read n-gate commentary on the comments here
uptownfunk··on The man who killed Google Search?
Is it that bad to have been a mgmt consultant? My goodness
uptownfunk··on Tell HN: Ever think of applying to YC? Do it this weekend for S24
My friend is part of a team of PhDs working on hard tech research problems without much interest in becoming a viable business (in the sense of counting dollars). It seems like YC would not be the right fit for them, is that correct? They seem to have gotten interest from other VCs but they have the impression that YC is more of a traditional firm focused on startups that are very close to revenue or are post revenue
uptownfunk··on Ask HN: What framework should I learn?
Go/Gin React PostgreSQL
uptownfunk··on Language models are Super Mario: Absorbing abilities from homologous models
Does this imply that some type of decentralized training mechanism is possible? Like an accumulation for ML models. I suspect in the limit You will just have even more massive models which will require even more demand on the hardware. I also wonder if new capabilities emerge from the merging that are not present in any one model.
uptownfunk··on JetMoE: Reaching LLaMA2 performance with 0.1M dollars
Where are they hosted?
uptownfunk··on JetMoE: Reaching LLaMA2 performance with 0.1M dollars
Well, it's interesting to think about how much has been invested into BigModel companies (Anthropic, Perplexity, OpenAI) when it's very rapidly becoming commoditized.
uptownfunk··on Ask HN: Most efficient way to fine-tune an LLM in 2024?
Also interested in this. Does this task really require such specialized knowledge?
uptownfunk··on Mathematician who made sense of the universe's randomness wins Abel Prize
My problem was always I took on too much so I had surprising breadth. I could find connections between many areas. I wish I had just focused on one or two things and gone very very deep. I would probably be a more fulfilled academic today if I was able to do that instead of an engineering manager.
uptownfunk··on Mathematician who made sense of the universe's randomness wins Abel Prize
A physical magazine would be nice. I just print papers out on my printer these days and mark em up with my pen of choice :)
uptownfunk··on Mathematician who made sense of the universe's randomness wins Abel Prize
The world needs more recognition of good mathematics and mathematicians. Really love the work quantum magazine does on covering mathematics. So many implications for the rest of the world.
uptownfunk··on Google's First Tensor Processing Unit: Architecture
What Google really needs to do is get into the 2nm EUV space and go sub 2nm. When they have the electro lithography (or whatever tech ASML has that prints on the chips) then you have something really dangerous. Probably a hardcore Google X moonshot type project. Or maybe they have 500mm sitting around to just buy one of the machines. If their tpu are really that good - maybe it is a good business - especially if they can integrate all the way to having their own fab with their own tech
uptownfunk··on Ask HN: How did you get yourself out of a rut?
There is always another chance. As long as your heart is beating, your body is functioning, there is hope, even for the hopeless.

Try and find a source of strength and connect with it, then it will give you the hope and strength you don’t have now. Or it may be a friend, a religion, God, a community, a historical figure, a living figure, that energy is out there and when you connect with it you will feel it again.

I hope you find it, sending a healthy portion of blessings your way.

uptownfunk··on Ask HN: How did you get yourself out of a rut?
I love love love this- you are 100% right

> shut off your phone, go outside for a couple weeks, no tech, no internet, nobody nagging or forcing you to do anything. And listen. To nature, to the environment, to what you think. Take with you a notebook and a pen, and write down your thoughts. Persist on not going online, and fight the addiction.

uptownfunk··on RStudio: Integrated development environment (IDE) for R
I think one of the most underrated pieces of software in modern history. Absolutely brilliant. Huge fan. I am glad to see it getting love. I’ve moved on from data science in a professional capacity but for some pet projects of mine it has been indispensable. I think managing the namespace was one non trivial concern (which may be resolved in modern versions). Otherwise very well built for data science applications. Interesting that it didn’t catch on for LLM training - I think a missed opportunity.
uptownfunk··on Intel to Receive $8.5B in Grants to Build Chip Plants
Isn’t that what they said about rockets?
uptownfunk··on Ask HN: SWEs – Are y'all worried about your jobs?
That’s because most debates are not won based on reason. In fact a large part of how the world works is mostly based on how you say something not what you say. Perhaps the world of engineering and mathematics (and subjects which strongly depend on these) are the only ones where reasoning is a stronger lever in an outcome (outside of perhaps economic incentives).
uptownfunk··on Google to use open source RISC-V for its custom AI silicon, TPU
Have they finalized the spec on vector related instruction set
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