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wjb3

1,925 karma · joined June 18, 2023

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wjb3··on Common Painkillers May Accelerate Antibiotic Resistance
Original paper - https://www.nature.com/articles/s44259-025-00144-w
wjb3··on The role of diet quality and adiposity in the pain experience
Patients with overweight or obesity who followed a 3-month weight-loss dietary intervention cut chronic musculoskeletal pain scores in half, independent of adiposity changes.
wjb3··on Is Fecal Transplantation Effective for Depression?
Original paper: https://www.frontiersin.org/journals/psychiatry/articles/10....
wjb3··on What Using Our Hands While Speaking Reveals About Our Brains
Original paper: https://journals.sagepub.com/doi/full/10.1177/09567976251331...
wjb3··on Memantine Boosts Social Functioning in Some Autism Cases
The findings were published online on October 1 in JAMA Network Open https://jamanetwork.com/journals/jamanetworkopen/fullarticle...
wjb3··on Exposure to Commonly Used Chemical Tied to Parkinson's Disease Risk
Original study: https://www.neurology.org/doi/10.1212/WNL.0000000000214174
wjb3··on Nicotinamide for Skin Cancer Chemoprevention
Details for the lay reader: https://www.npr.org/2025/09/17/nx-s1-5544145/vitamin-b3-can-...
wjb3··on Psychedelics for Eating Disorders?
Cannabis and psychedelics were rated as the most effective drugs for symptom relief by survey participants with eating disorders (EDs), including anorexia nervosa, bulimia nervosa, and binge eating disorder (BED). On the other hand, patients perceived prescription antidepressants as mainly providing benefits for overall mental health.
wjb3··on Responsiveness variability during anaesthesia and differences in brain structure
Patients who experienced accidental awareness under anesthesia tended to have larger volumes of frontal gray matter and stronger frontoparietal brain connections, potentially supporting continued conscious experience despite general anesthesia. I.e., larger frontal grey matter + stronger frontoparietal (functional) connections are associated with better preserved responsiveness, even when consciousness is suppressed (to some degree) by anaesthesia.
wjb3··on Meal timing and associations with morbidity, genetic profiles, and mortality
Later breakfast time was consistently associated with having physical and mental health conditions such as depression, fatigue, and oral health problems.
wjb3··on AI School Is in Session
This is the future: redesign assessment (process logs, oral defenses, live builds), teach motivation + metacognition, and ensure access to premium AI, so tools amplify learning instead of replacing it.
wjb3··on Consumption of Low- and No-Calorie Artificial Sweeteners and Cognitive Decline
In adjusted analyses, people who consumed the highest total amounts of these sweeteners had a 62% faster decline in overall thinking and memory skills, equivalent to about 1.6 years of aging, than those consuming the lowest amount.
wjb3··on Poison Pills?
Original paper - https://ehjournal.biomedcentral.com/articles/10.1186/s12940-...
wjb3··on Microbial metabolite repairs liver injury by restoring hepatic lipid metabolism
I find the dish detergent hypothesis more compelling than I used to - before moving to Australia. Here, I've noticed that almost nobody rinses the dishes after washing them (something I have always done). Curious what others do in different locations/cultures. Seems pretty obvious that consuming surfactants, triclosan, phthalates, alkaline agents, synthetic fragrances and dyes is not a great gut health strategy.
wjb3··on Screen time and emotional problems in kids: A vicious circle?
I used to think we’d adjust. Sure, the rise of screens was fast and destabilizing—but I believed young people would adapt, and that calling it a crisis was just the latest round of moral panic. A generational overreaction, like the Beatles or comic books or video games before them. But as the data pile up, I find myself shifting.

Now, I think we will likely look back on this era the way we now view ubiquitous cigarette smoking: What were we thinking? It should have been obvious.

We don’t need to adjust to the smoke. We need a public health response that makes the air clear again—where the very idea of “screen childhood” feels as strange to future parents as a cigarette in a stroller. Not a ban. Not panic. But a serious, data-driven cultural shift.

wjb3··on Researchers who 'pivot' into new fields should not be given a citation penalty
I once sat in on a hiring committee where candidates with broad, interdisciplinary CVs were treated with subtle derision—as though curiosity across domains was a sign of unseriousness.

As someone who’s always been promiscuous with my curiosity, I was surprised—and disappointed.

That experience stuck with me. It challenged my once-naive belief that academia was a place that welcomed intellectual breadth.

So you can imagine my quiet hope when I saw Nature publish this: an editorial calling for an end to the "pivot penalty"—the career cost researchers pay when they step outside their disciplinary silos.

The piece notes that interdisciplinary teams often produce more meaningful work (even if it takes longer) and that global problems demand cross-domain insight. It also highlights studies showing that Nobel laureates are more likely to collaborate across fields, and calls for evaluation systems to catch up.

Maybe—just maybe—we’re starting to value the spark that comes from recombining ideas that don’t obviously belong together.

And maybe that means a few more of us can return to the kind of scholarly life we once imagined.

wjb3··on Neuron–Astrocyte Associative Memory
"These process-to-process communications likely occur in the brain and could help explain its impressive memory processing capabilities."
wjb3··on Certainty Transfer Effect
TL;DR:

"If this was just about technology, that would be interesting enough. But technology doesn’t operate in isolation. It shapes culture, which shapes institutions, which shapes incentives—until you end up with a whole epistemic ecosystem where uncertainty is treated as something shameful."

wjb3··on Could a Quantum ASI Overcome Self-Reference and Infinite Regress?
and https://www.cs.miami.edu/home/burt/learning/Csc670.052/pR249...
wjb3··on Could a Quantum ASI Overcome Self-Reference and Infinite Regress?
also - https://philsci-archive.pitt.edu/5439/1/Decoherence_Essay_ar...
wjb3··on Could a Quantum ASI Overcome Self-Reference and Infinite Regress?
the link to Birkhoff, G., & von Neumann, J. (1936). The logic of quantum mechanics. Annals of Mathematics, 823-843. is paywalled, but...

https://ia800905.us.archive.org/21/items/TheLogicOfQuantumMe...

wjb3··on Could a Quantum ASI Overcome Self-Reference and Infinite Regress?
"...it is not clear to me that the AI will be any better at understanding itself than any other conscious entity, and that lack of clarity could be more problematic than the inevitable misalignment of its programmed ethos."

Haven't heard anybody say that before.

wjb3··on The reason sleep-deprivation kills is in the gut
Agreed; title changed from source original
wjb3··on Commercial toilets emit energetic and rapidly spreading aerosol plumes (2022)
The bottom line: When you flush the toilet, there is an invisible aerosolized plume that spews any pathogen residing in the bowl into the air. While it is theoretically possible to become infected, more so when someone with a highly contagious disease has previously used the toilet, it is unlikely in most cases.

https://www.msn.com/en-us/health/medical/can-you-get-sick-fr...

wjb3··on Ejaculation Frequency and Prostate Cancer Risk
"...most of the studies hint at an inverse association, suggesting a potential protective role of frequent ejaculation"
wjb3··on Uniform Outcome Measurement Approach for Early Interventions of ASD
The study evaluates the effectiveness of the Brief Observation of Social Communication Change (BOSCC) as a standardized measure for assessing social communication skills across different intervention models for children with autism. Findings suggest that BOSCC can effectively measure changes in broad social communication abilities, allowing for better comparison across various intervention studies.
wjb3··on Carvings at Gobekli Tepe may be oldest calendar
[DUPE] https://news.ycombinator.com/item?id=41174729
wjb3··on Oldest calendar discovered in ancient temple
The site, known as Karahan Tepe, features stone structures aligned with celestial events like solstices and equinoxes, suggesting its use as a solar calendar.
wjb3··on Brain 'chimeroids' reveal person-to-person differences rooted in genetics
How do you think this technique could change our understanding of neurological disorders and personalized medicine? What ethical considerations should we keep in mind as this research progresses?
wjb3··on Trying to outrun her disease, researcher creates powerful epigenetic editor
What do you think are the biggest challenges and potential breakthroughs in using CRISPR for epigenetic editing? Could this approach revolutionize treatment for other genetic disorders as well?
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