It's plausible that this would negatively impact transgender women, considering dementia is associated with lower testosterone levels in men.
Please see: https://news.ycombinator.com/item?id=12708367
Please see: https://news.ycombinator.com/item?id=12708367
That's not necessarily a relevant comparison since the goal of HRT in trans women is not simply to lower testosterone, but also to raise estrogen (and sometimes progesterone) to female levels.
Trans women on HRT are not hormonally like cis men (including men on ADT), so extrapolating any effect of sex hormone from cis men to trans women is going to lead you astray.