"Increase telomere length" - is that even doable at the moment?
"Increase GABA" - I thought oral GABA supplements do not cross the blood-brain barrier?
Others sure are doable:
"Enhance leptin sensitivity" and "Increase autophagy" can be done AFAIK by intermittent fasting (even better, water fasting several days).
"Enhance mitochondnal function and biogenesis" - any kind of sports, CoQ10 and photobiomodulation come to mind (BTW I've heard of a pilot study where they greatly improved Alzheimer's for ~2 weeks after a treatment with a near-infrared radiation helmet).
"Reduce homocysteine" - supplement B12 (ideally, methylcobalamin).
Most of the mentioned hormones (upper half of right column) can be optimized with medication.
"Reduce inflammation" is likely very beneficial, but tricky; eliminate all foods that cause autoimmune reactions?