Judging by the PC's history of transitioning from 32-bit to 64-bit x86 (still not complete after 20 years), and from x86 to ARM (Windows on ARM is at 14% market share after more than 10 years)… well. I'm just a
bit skeptical.
Though to be fair, it all depends on the hardware. Windows on ARM struggled not just because it wasn't x86 but because nobody was making powerful-enough ARM processors. Now that those processors are starting to arrive, it's supposedly going to take off in the next few years. …Probably only on the low end, though. But you never know.
And RISC-V? Maybe someday.