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Doesn’t niacin lead to prettt severe hot flashes / flushing of the face and extremities? I know someone who was told to take it for cholesterol (I think) and it sounded painful!

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Niacin mega-doses have been used for decades to reduce lipids, triglycerides, etc. and yes when you take 1 gram it will causes a painful flushing.

However to simply raise NAD+ levels you can take as little as 100mg

Yes, too much niacin can make your entire body flush with a burning sensation.

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