Depending on where you live, you might have to wait six months to a year to go on employment after you quit a job or are fired for cause, as opposed to being laid off.
Unemployment has also been severely cut, and the term severely shortened since the days of the 99ers. There's really not any government support other than unemployment available for able-bodied single people (they've even cut food stamps recently, which is one of the cruelest things you can do in a depressed economy.) Of course, if you become homeless the IRS will definitely leave you alone.